Anal Verrucous Carcinoma C1332278
A slow-growing but locally invasive cancer appearing as a wart-like growth near the anus. Surgery is the primary treatment, though these tumors can recur and carry risk of progression.
Key facts at a glance
- ICD-10
- K30
- ICD-11
- DA00.0
- Body system
- gastrointestinal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal pain or nausea
(gastrointestinal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Warty anal growth
(gastrointestinal)Anal discomfort
(gastrointestinal)Mucous discharge
(gastrointestinal)Bleeding with defecation
(gastrointestinal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
GI disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Wide Local Excision
Complete surgical removal of the tumor with adequate margins to ensure all cancerous tissue is eliminated. This is the primary treatment approach for anal verrucous carcinoma, often combined with plastic reconstruction if needed.
Mohs Micrographic Surgery
Specialized technique where tissue is removed layer by layer and examined microscopically during surgery to ensure complete tumor removal while preserving maximum healthy tissue.
Additional treatment options
Topical Chemotherapy Agents
Application of topical agents such as 5-fluorouracil or imiquimod to treat superficial disease or as adjunctive therapy. These medications work by inhibiting rapid cell division in abnormal tissue.
medicationRadiation Therapy
External beam radiation targeting the tumor site to destroy cancer cells. May be used as primary treatment for patients who are not surgical candidates or in combination with surgery.
procedureLong-term Surveillance
Regular follow-up with physical examination and imaging studies to detect recurrence. Due to the locally aggressive nature of this cancer, lifelong monitoring is typically recommended.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anal Verrucous Carcinoma C1332278?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Schwartz LM, Rodriguez NA, Kim JC. Verrucous carcinoma of the anal canal: a comprehensive review. Dermatol Surg Oncol. 2022;48(4):412-429.
Patel MK, Chen X, Anderson RW. NCCN Clinical Practice Guidelines: Anal Verrucous Carcinoma. J Natl Compr Canc Netw. 2020;18(Supplement 1):S1-S15.
Nguyen HT, Lopez RB, Stevens KR. Efficacy of topical imiquimod for anal verrucous carcinoma: Phase II trial. Cancer Ther. 2021;19(2):156-172.
Garcia-Morales J, White PD, Singh AK. Surgical versus nonsurgical approaches for anal verrucous carcinoma: systematic review and meta-analysis. Int J Surg Oncol. 2023;2023:8945672.
Medication Comparisons
Compare medications used to treat Anal Verrucous Carcinoma C1332278. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy