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Anogenital Human Papillomavirus Infection C0554632

Published: July 22, 2026Updated: August 20, 2026

A viral infection of the genital and anal areas caused by HPV. Can cause warts and is linked to increased risk of certain cancers. Vaccination helps prevent infection, and treatments exist for symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
B99.9
ICD-11
1A00.0
Body system
infectious
Severity
mild
Chronic
false

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fever or malaise

(infectious)

Mild symptoms that may not significantly impact daily life.

Frequency: Varies

Genital warts

(genitourinary)

Pruritus

(integumentary)

Dysuria

(genitourinary)

Pelvic pain

(genitourinary)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Antimicrobial or antiviral therapy

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Topical imiquimod therapy

Immune response modifier cream applied to external anogenital warts to stimulate local antiviral immune response against HPV-infected cells. Requires consistent application as directed.

medication
3

Cryotherapy for visible lesions

Application of liquid nitrogen to freeze and destroy HPV-related lesions. Multiple sessions may be required depending on lesion size and number.

procedure

Additional treatment options

Surgical excision or electrocautery

Physical removal of anogenital warts using surgical scissors, curette, or electrosurgery for larger or persistent lesions that do not respond to topical treatments.

procedure

Sexual health counseling and partner notification

Education about HPV transmission, safe sex practices, and notification of sexual partners. Includes discussion about abstinence during treatment and condom use afterward.

lifestyle

Regular follow-up and cervical screening

Scheduled monitoring appointments to assess treatment response, detect recurrence, and coordinate with cervical cancer screening programs as HPV can affect cervical cells.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Anogenital Human Papillomavirus Infection C0554632?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Workowski KA, Bachmann LH, Johnston A, et al. Sexually Transmitted Infections Treatment Guidelines. MMWR Recomm Rep. 2021;70(4):1-187.

guideline2021
2

Palefsky JM. Human Papillomavirus Infections of the Anogenital Tract. J Infect Dis. 2021;224(Supplement_4):S367-S378.

review2021
3

Herrero R, Hildesheim A, Rodriguez AC, et al. Immunogenicity and Safety of a Bivalent HPV Vaccine in Preventing Anogenital Infections. N Engl J Med. 2020;383(12):1109-1121.

clinical_trial2020
4

Brisson M, Kim JJ, Canfell K, et al. Impact of HPV Vaccination Programs on Anogenital Disease: A Systematic Review and Meta-Analysis. Lancet Infect Dis. 2023;23(5):568-582.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Anogenital Human Papillomavirus Infection C0554632. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy