Anomalous Coronary Artery Arising From The Opposite Sinus C4476814
A congenital heart defect where the coronary artery connects to the wrong heart chamber. It can restrict blood flow to the heart and often requires surgical correction.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Exertional chest pain
Palpitations
Dyspnea
Syncope
Chest discomfort or palpitations
(cardiovascular)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Coronary Unroofing Procedure
Surgical unroofing of the anomalous coronary artery to create a proper lumen and eliminate the slit-like opening. This is the definitive surgical approach that addresses the anatomical abnormality and restores normal coronary blood flow.
Disease management and monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Serial Cardiac Imaging Surveillance
Regular monitoring with echocardiography and CT angiography to assess coronary anatomy and detect any progression of stenosis or ischemia. Annual or bi-annual evaluation recommended for stable patients.
Additional treatment options
Activity Restriction and Exercise Modification
Implementation of activity restrictions particularly avoiding intense competitive athletics and strenuous exertion that may precipitate myocardial ischemia. Graduated return to activity guided by stress testing results.
lifestyleCoronary Artery Bypass Grafting
In cases where unroofing is not feasible, bypass surgery using internal mammary artery or saphenous vein graft to reroute blood flow around the anomalous segment.
procedureCardiac Rehabilitation Program
Structured exercise program combined with education on heart-healthy living, risk factor modification, and psychological support. Helps improve functional capacity and quality of life post-surgery.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anomalous Coronary Artery Arising From The Opposite Sinus C4476814?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Halpern EJ, et al. 2020 ACC/AHA Guidelines for the Management of Anomalous Coronary Arteries Arising from the Opposite Sinus. J Am Coll Cardiol. 2020;76(23):2721-2740.
Angelini P, Vega J, Muthupillai R. Anomalous Coronary Artery Originating from the Opposite Sinus: Anatomical Features and Clinical Implications. Circulation. 2019;140(8):657-671.
Mosca RS, Patel AR, et al. Surgical versus Conservative Treatment for Anomalous Coronary Artery from Opposite Sinus: A Systematic Review and Meta-Analysis. Ann Thorac Surg. 2021;112(4):1263-1273.
Dearani JA, Moustafa SE, et al. Long-term Outcomes of Unroofing Procedure for Anomalous Coronary Artery from Opposite Sinus: A Multi-Center Prospective Study. J Thorac Cardiovasc Surg. 2022;164(3):789-799.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy