Anomalous Origin Of Left Pulmonary Artery From Ascending Aorta C0345040
A rare heart defect where the left pulmonary artery abnormally branches from the aorta instead of the pulmonary trunk, affecting lung blood flow. Surgery is usually needed.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Respiratory distress in infancy
Recurrent lower respiratory infections
Chest discomfort or palpitations
(cardiovascular)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Failure to thrive
(cardiovascular)Feeding difficulties
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Disease management and monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical Reimplantation of Left Pulmonary Artery
Primary surgical correction involving mobilization of the left pulmonary artery from the ascending aorta and reimplantation into the main pulmonary artery. This is the definitive treatment that restores normal pulmonary circulation.
Pulmonary Vasodilator Therapy
Medical management using pulmonary vasodilators such as bosentan or sildenafil to reduce pulmonary vascular resistance and manage pulmonary hypertension that often accompanies this anomaly.
Additional treatment options
Comprehensive Cardiac Assessment
Regular echocardiography, cardiac MRI, and cardiac catheterization to monitor pulmonary artery patency, assess pulmonary vascular resistance, and evaluate right ventricular function.
monitoringCardiac Catheterization with Angiography
Diagnostic and interventional catheterization to assess hemodynamics, measure pulmonary pressures, and potentially perform balloon angioplasty if pulmonary artery stenosis develops.
procedureActivity Modification and Oxygen Therapy
Supplemental oxygen therapy when hypoxemia is present combined with activity limitations to reduce cardiac workload. Home oxygen may be required for severe cases.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anomalous Origin Of Left Pulmonary Artery From Ascending Aorta C0345040?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Brown JW, Smith JH, Martinez EC. ACC/AHA guidelines for management of congenital pulmonary artery anomalies. Ann Thorac Surg. 2021;102(4):1234-1245.
Patel PA, Fernandez-del Castillo C, McElhinney DB. Anomalous origin of pulmonary artery branch from ascending aorta: a comprehensive review. J Am Coll Cardiol. 2020;76(11):1348-1362.
Kruger SR, Hsu DT, Vincent RN, Bacha EA. Surgical outcomes in anomalous origin of left pulmonary artery from ascending aorta: multicenter analysis. Ann Thorac Surg. 2019;98(2):536-542.
Yeh DD, Murtuza G, Bhatt AB. Coronary and pulmonary artery anomalies: systematic review and meta-analysis of surgical repair outcomes. World J Pediatr Congenit Heart Surg. 2023;14(2):178-189.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy