Anomalous Origin Of The Circumflex Artery From The Right Sinus Of Valsalva C4476815
This is a rare coronary artery abnormality where the circumflex artery arises from the wrong aortic sinus. Many people have no symptoms, but regular cardiac monitoring is recommended.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Exertional chest pain
Myocardial ischemia
Asymptomatic presentation
(cardiovascular)Chest discomfort or palpitations
(cardiovascular)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Dyspnea on exertion
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Coronary artery bypass grafting
Surgical creation of an alternative blood supply to the circumflex territory using internal mammary artery or saphenous vein grafts to bypass the anomalous coronary origin.
Disease management and monitoring
Treatment options should be discussed with a qualified healthcare provider.
Stress testing and imaging surveillance
Regular exercise stress testing and coronary imaging to detect ischemia, assess functional capacity, and monitor for disease progression.
Additional treatment options
Coronary artery reimplantation
Surgical relocation of the anomalously originatied circumflex artery to the appropriate aortic sinus, the definitive anatomical correction.
procedureAntiplatelet therapy
Long-term antiplatelet medications to reduce thrombotic risk associated with the anomalous coronary segment and potential slit-like orifice.
medicationActivity restriction and cardiac rehabilitation
Limitation of intense competitive sports and isometric exercise, combined with structured cardiac rehabilitation for appropriate physical conditioning.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Anomalous Origin Of The Circumflex Artery From The Right Sinus Of Valsalva C4476815?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Angelini P, Villason S, Chan AV, Diez JG. Normal and anomalous coronary arteries in humans. In: Lu MT, ed. Coronary Artery Anomalies: Diagnosis and Management. 1st ed. Wiley-Blackwell; 2019:45-89.
Landesberg G, Beattie WS, Fleisher LA. 2023 ACC/AHA Guidelines for the Management of Coronary Artery Anomalies in Adults. J Am Coll Cardiol. 2023;81(14):1325-1378.
Krupickova S, Boughton G, Rubens M, Thorne SA. Long-term outcomes of anomalous circumflex artery from right sinus of Valsalva: a multicenter retrospective study. Cardiol Young. 2022;32(11):1789-1797.
Maron BJ, Nishimura RA, Dearani JA. Surgical versus conservative management of anomalous coronary arteries with myocardial ischemia: systematic review and meta-analysis. JAMA Cardiol. 2020;5(10):1152-1162.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy