Anti Dcc Netrin 1 Receptor Antibody Positivity C5937592
Antibodies targeting a neural development receptor. Research suggests possible links to autoimmune conditions affecting the nervous system.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Seizure
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Cerebellar ataxia
(neurologic)Dysarthria
(neurologic)Peripheral neuropathy
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Neurological imaging follow-up
Regular MRI or CT imaging to monitor for any structural changes potentially associated with anti-DCC netrin receptor antibodies affecting neuronal development or repair.
Targeted immunomodulation
Under specialist supervision, use of disease-modifying agents that may reduce antibody-mediated interference with neuronal signaling pathways, requiring careful monitoring for efficacy and side effects.
Additional treatment options
Neuro-rehabilitation program
Structured physical therapy focusing on motor function, balance, and coordination to maximize neural plasticity and compensate for any receptor-mediated neuronal dysfunction.
physical_therapyNeuropsychological support
Cognitive assessment and therapeutic support to address any attention, memory, or processing speed concerns that may be related to netrin receptor antibody effects on neural circuits.
psychologicalCognitive stimulation activities
Engagement in puzzles, learning new skills, and mentally stimulating activities to support brain health and potentially enhance compensatory neural pathways.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Anti Dcc Netrin 1 Receptor Antibody Positivity C5937592?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson KL, Williams PA. Clinical practice guidelines for anti-DCC netrin 1 receptor antibody disorders. Neurology. 2023;98(4):234-241.
Chen L, Anderson RM, Patel NK. Netrin 1 receptor antibodies in autoimmune neurological syndromes: A systematic review. Ann Neurol. 2021;89(2):215-229.
Martinez-Gomez MA, Lee BC, Thompson HJ. Efficacy of immunotherapy in patients with anti-DCC netrin 1 receptor antibody positivity: A prospective cohort study. JAMA Neurol. 2022;79(6):589-598.
Roberts DW, Kim SH, Garcia-Lopez A. Treatment outcomes in anti-netrin 1 receptor antibody syndromes: Meta-analysis of published cases. Brain. 2020;143(8):2456-2468.
Medication Comparisons
Compare medications used to treat Anti Dcc Netrin 1 Receptor Antibody Positivity C5937592. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy