Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis C2717865
A group of autoimmune disorders causing blood vessel inflammation. It primarily affects adults and can damage organs. Treatment typically involves immunosuppressive medications and corticosteroids.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Mononeuritis multiplex
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Hematuria
(urinary)Weight loss
(systemic)Sinusitis
(ENT)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Induction immunosuppression
Combination therapy with high-dose corticosteroids and either rituximab or cyclophosphamide to rapidly suppress ANCA-mediated vasculitic inflammation and prevent organ damage.
Plasma exchange
Removal of circulating ANCA antibodies and inflammatory mediators, particularly indicated for severe renal involvement or pulmonary hemorrhage in active vasculitis.
Additional treatment options
Maintenance immunosuppression
Long-term lower-dose immunosuppression with agents such as azathioprine, methotrexate, or rituximab to maintain remission and prevent disease flares.
medicationOrgan-specific surveillance
Regular monitoring of renal function, lung imaging, and ANCA titers to detect organ involvement and early signs of disease relapse requiring treatment adjustment.
monitoringCardiovascular risk reduction
Lifestyle modifications including smoking cessation, regular exercise, and blood pressure management to reduce increased cardiovascular risk associated with vasculitis and its treatments.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis C2717865?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Suppiah R, Robson JC, Luqmani RA. EUVAS consensus guidelines for ANCA-associated vasculitis. Rheumatology. 2021.
Kitching AR, Anders HJ, Basu N. ANCA-associated vasculitis. Nat Rev Dis Primers. 2020.
Stone JH, Merkel PA, Spiera R. Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med. 2010.
Park J, Chang HS, Park SY. Avacopan for ANCA-associated vasculitis: a systematic review and meta-analysis. Kidney Int. 2023.
Medication Comparisons
Compare medications used to treat Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis C2717865. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy