Antistreptolysin O Antibody Positivity C5937143
Antistreptolysin O (ASO) antibody positivity is a lab marker showing recent streptococcal infection. It helps diagnose conditions like rheumatic fever. Treatment targets the underlying infection with antibiotics if needed.
Key facts at a glance
- ICD-10
- B99.9
- ICD-11
- 1A00.0
- Body system
- infectious
- Severity
- mild
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fever or malaise
(infectious)Mild symptoms that may not significantly impact daily life.
Frequency: Varies
Sore throat
(infectious)Fever
(infectious)Tonsillar exudates
(infectious)Cervical lymphadenopathy
(infectious)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antimicrobial or antiviral therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
ASO Titer Follow-up Testing
Serial measurement of antistreptolysin O titers to monitor decline over time, typically every 6-12 months until normalization.
Penicillin-Based Antibiotic Therapy
When active streptococcal infection is confirmed, antibiotic treatment with penicillin or appropriate alternatives eliminates the source of antigenic stimulation.
Additional treatment options
Rheumatic Fever Screening
Clinical monitoring for signs of rheumatic fever including carditis, arthritis, chorea, and skin findings in the months following infection.
monitoringInfection Prevention Measures
Practice good hand hygiene, avoid sharing utensils, and maintain respiratory precautions to prevent streptococcal transmission.
lifestyleNSAIDs for Symptom Relief
Non-steroidal anti-inflammatory medications may be used if arthralgia or low-grade inflammation accompanies elevated ASO titers.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Antistreptolysin O Antibody Positivity C5937143?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Shulman ST, Bisno AL, Clegg HW, et al. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis. Clin Infect Dis. 2022.
Cunningham MW. Pathogenesis of group A streptococcal infections and their sequelae. Curr Opin Infect Dis. 2020.
Martin WJ, Steer AC, Smeesters PR, et al. Post-streptococcal glomerulonephritis: a systematic review of its epidemiology and risk factors. Lancet Infect Dis. 2018.
Ferrieri P, Dajani AS, Wannamaker LW. Natural history of streptococcal infections. In: Textbook of Pediatric Infectious Diseases. Philadelphia: Elsevier; 2016.
Medication Comparisons
Compare medications used to treat Antistreptolysin O Antibody Positivity C5937143. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy