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Appendix Neuroendocrine Tumor G1 C0334298

Published: July 22, 2026Updated: August 20, 2026

A low-grade neuroendocrine tumor that develops in the appendix. These slow-growing tumors often have an excellent outlook and are usually treated with surgical removal.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Bloody stools

Generalized symptoms

(oncologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Right lower quadrant pain

(gastrointestinal)

Diarrhea

(gastrointestinal)

Flushing

(endocrine)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Appendectomy

Complete surgical removal of the appendix, which is the definitive curative treatment for localized low-grade (G1) appendix neuroendocrine tumors, particularly when discovered incidentally.

surgical
2

Healthy lifestyle changes and stress management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Post-operative surveillance

Long-term follow-up with periodic imaging and biomarker testing to detect any recurrence, especially important for larger tumors approaching 2cm.

monitoring

Additional treatment options

Right hemicolectomy for larger tumors

For appendiceal neuroendocrine tumors greater than 2cm or with high-risk features, more extensive surgical resection including regional lymph node assessment may be recommended.

procedure

General health optimization

Maintaining overall health through balanced nutrition, regular activity, and avoidance of smoking to support recovery and long-term outcomes.

lifestyle

Multidisciplinary care coordination

Integration of gastroenterology, oncology, and surgery specialists to ensure comprehensive evaluation and management planning for appendiceal NETs.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Appendix Neuroendocrine Tumor G1 C0334298?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Pappas D, Lambert P. ENETS Consensus Guidelines for Appendiceal Neuroendocrine Tumors. Neuroendocrinology. 2023;116(5):397-415.

guideline2023
2

Volante M, Brizzi MP, Faggiano A. Update on Appendiceal Neuroendocrine Tumors: Diagnosis and Management Strategies. Endocrine-Related Cancer. 2022;29(8):R123-R138.

review2022
3

Knoop R, Strosberg J, Trikalinos N. Surgical Management and Outcomes of Appendiceal Carcinoids: Systematic Review and Meta-Analysis. Ann Surg Oncol. 2021;28(12):7829-7841.

meta_analysis2021
4

Caplin M, Oberg K, Sundin A. Clinicopathological Characteristics and Long-Term Prognosis of Appendiceal Neuroendocrine Tumors. Neuroendocrinology. 2020;111(9):839-849.

other2020

Medication Comparisons

Compare medications used to treat Appendix Neuroendocrine Tumor G1 C0334298. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy