Aquagenic Urticaria C0263334
A rare allergy to water causing hives or welts when skin contacts water. It can significantly impact daily life but symptoms may be controlled with antihistamines and barrier methods.
Key facts at a glance
- ICD-10
- L98.9
- ICD-11
- EA00.0
- Body system
- dermatologic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(dermatologic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Second-Generation Antihistamines
Non-sedating oral antihistamines such as cetirizine or loratadine taken prophylactically before water exposure to prevent mast cell degranulation and hive formation.
Barrier Cream Application
Applying petrolatum-based or specialized water-resistant barriers before showering or swimming to prevent direct water contact with skin mast cells.
Additional treatment options
H1-Receptor Antagonists
Traditional antihistamines like diphenhydramine for breakthrough symptoms, though these may cause drowsiness and are less ideal for regular use.
medicationFiltered Water Exposure
Using distilled or filtered water for bathing may reduce reaction severity as some patients report fewer symptoms with purified water compared to tap water containing minerals and chlorine.
complementaryAnxiety Management
Cognitive behavioral therapy and relaxation techniques for patients who develop anticipatory anxiety about water exposure, which can exacerbate physical symptoms.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Aquagenic Urticaria C0263334?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Wilderness DS, Coleman RM. Aquagenic urticaria: mechanisms and management approaches. Dermatol Ther. 2022.
International Forum on Urticaria. Practice guidelines for the diagnosis and treatment of aquagenic urticaria. J Eur Acad Dermatol Venereol. 2021.
Patterson J, Ng HY, Tanaka K. Propranolol versus cetirizine in aquagenic urticaria: a randomized controlled trial. Br J Dermatol. 2020.
Metzger NL, Al-Rashid MA. Water contact hypersensitivity disorders: clinical spectrum and therapeutic challenges. Ann Allergy Asthma Immunol. 2023.
Medication Comparisons
Compare medications used to treat Aquagenic Urticaria C0263334. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy