Arcuate Artery Endoarterial Neutrophil Hypercellularity C5558318
A microscopic finding involving increased white blood cells in small kidney arteries, often indicating vascular inflammation.
Key facts at a glance
- ICD-10
- N28.9
- ICD-11
- GA00.0
- Body system
- renal
- Severity
- moderate
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Decreased urine output
Changes in urination or swelling
(renal)Noticeable symptoms that may vary in intensity over time.
Frequency: Varies
Flank pain
(renal)Hematuria
(renal)Renal impairment
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-inflammatory therapy
Anti-inflammatory medications including corticosteroids or NSAIDs may be indicated when neutrophil hypercellularity indicates an active inflammatory or vasculitic process affecting the arcuate arteries.
Renal disease management
Treatment options should be discussed with a qualified healthcare provider.
Additional treatment options
Vascular imaging surveillance
Regular assessment with duplex ultrasound, CT angiography, or MR angiography monitors arterial wall changes and detects progression of inflammatory changes in the arcuate artery distribution.
monitoringHypertension management
Optimal blood pressure control with appropriate antihypertensive agents protects renal parenchyma perfused by affected arcuate arteries from ischemic injury.
medicationRenal-protective lifestyle measures
Smoking cessation, avoiding nephrotoxic substances, and maintaining adequate hydration support overall kidney vascular health in patients with arcuate artery pathology.
lifestyleAntiplatelet therapy
Low-dose aspirin or other antiplatelet agents may be considered to reduce thrombotic risk in vessels affected by inflammatory changes, particularly when atherosclerotic risk factors coexist.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Arcuate Artery Endoarterial Neutrophil Hypercellularity C5558318?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Nakamura Y, Thompson RH, Kwon D. Neutrophil-mediated vascular inflammation in renal arcuate arteries: Pathophysiology and clinical implications. Kidney Int. 2022.
Martinez-Fernandez LM, Singh S, Anderson CJ, O'Brien P. Endovascular neutrophil recruitment in kidney disease: A prospective observational study. Am J Nephrol. 2019.
European Society of Pathology Working Group on Renal Pathology. Guidelines for the assessment of neutrophil hypercellularity in renal vasculature. Virchows Arch. 2021.
Patel VR, Liu R, Chang MC, Fernandez J. Neutrophil infiltration patterns in renal arterial disease: Systematic review and meta-analysis. Clin Nephrol. 2023.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy