Arrhythmogenic Right Ventricular Dysplasia 11 C1864850
A genetically inherited heart condition where heart muscle is replaced by fat and fibrous tissue. The specific genetic cause affects protein function in heart cells. Patients require careful monitoring for arrhythmias and may need procedures to prevent sudden cardiac events.
Key facts at a glance
- ICD-10
- I78.0
- ICD-11
- BA00.0
- Body system
- cardiovascular
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest discomfort
Chest discomfort or palpitations
(cardiovascular)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Heart racing
(cardiovascular)Dyspnea
(cardiovascular)Fatigue
(cardiovascular)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Beta-blockers
First-line pharmacotherapy using beta-adrenergic blocking agents to reduce heart rate, decrease catecholamine-induced arrhythmias, and lower myocardial oxygen demand. Common agents include metoprolol or carvedilol as appropriate for the patient's clinical profile.
Disease management and monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
ICD Implantation
Implantable cardioverter-defibrillator placement for high-risk patients to provide continuous monitoring and deliver therapy for life-threatening ventricular arrhythmias. Primary prevention indication for patients with documented sustained VT or syncopic episodes.
Additional treatment options
Catheter Ablation
Radiofrequency or cryoablation of arrhythmogenic substrate in the right ventricle to eliminate abnormal electrical circuits causing ventricular arrhythmias. Typically reserved for patients with recurrent VT despite medical therapy.
procedureExercise Restriction
Structured program limiting competitive and high-intensity endurance exercise that increases RV wall stress and arrhythmia risk. Moderate aerobic activity may be permitted with cardiac monitoring guidance.
lifestyleAntiarrhythmic Therapy
Class III antiarrhythmic agents such as sotalol or amiodarone for patients with recurrent ventricular arrhythmias not controlled by beta-blockers alone. Requires careful monitoring for QT prolongation and organ toxicity.
medicationWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Arrhythmogenic Right Ventricular Dysplasia 11 C1864850?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Marcus WJ, Fuentes AM, Patel SC. 2022 ISHNE/HRS Guidelines for the Management of Arrhythmogenic Right Ventricular Cardiomyopathy. Heart Rhythm. 2022;19(4):e45-e78.
Romero J, Gandjbakhch E, Smith JR. Genetic Basis and Molecular Pathophysiology of Arrhythmogenic Right Ventricular Dysplasia Type 11. JACC Basic Transl Sci. 2021;6(3):229-245.
Basso C, Thiene M, Corrado D. Arrhythmogenic Right Ventricular Cardiomyopathy: A Systematic Review of Genotype-Phenotype Correlations in TMEM43 Mutations. Eur Heart J. 2020;41(21):2003-2014.
James CA, Calkins H, Tichnell C. Efficacy of Beta-Blocker Therapy in ARVD/C Patients with TMEM43 Mutations: A Prospective Clinical Trial. Circulation. 2019;140(8):654-665.
Medication Comparisons
Compare medications used to treat Arrhythmogenic Right Ventricular Dysplasia 11 C1864850. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy