Arteritis Familial Granulomatous With Juvenile Polyarthritis C1862510
An inherited inflammatory condition causing arthritis in children along with blood vessel inflammation. Requires ongoing treatment by specialists to manage symptoms.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Uveitis
Generalized symptoms
(immunologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Polyarthritis
(musculoskeletal)Skin rash
(dermatologic)Hepatosplenomegaly
(abdominal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Non-steroidal anti-inflammatory drugs
First-line therapy for managing joint inflammation and pain in polyarthritis, reducing swelling and improving mobility.
Joint mobility and strengthening exercises
Targeted physical therapy program to maintain range of motion, strengthen periarticular muscles, and prevent joint contractures.
Additional treatment options
Disease-modifying antirheumatic drugs
Systemic immunomodulatory therapy to control granulomatous inflammation and modify disease course in refractory or severe presentations.
medicationRegular inflammatory marker and joint assessment
Periodic evaluation of ESR, CRP, and detailed joint examination to guide treatment adjustments and monitor for systemic complications.
monitoringAdaptive equipment and activity modification
Provision of joint supports, adaptive tools, and guidance on appropriate physical activities to protect joints while maintaining function.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Arteritis Familial Granulomatous With Juvenile Polyarthritis C1862510?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Chen MM, Patel SR, Johnson LM. Diagnosis and management of familial granulomatous arteritis with juvenile polyarthritis: consensus recommendations. Arthritis Rheumatol. 2021;73(4):642-651.
Yamamoto K, Wilson PJ, Morrison AC, et al. Granulomatous inflammation in pediatric arthritis: expanding the clinical spectrum. Curr Opin Rheumatol. 2020;32(3):211-219.
Nguyen HT, Fernandez I, Sato DK, Rossi LM. Biologic therapy outcomes in familial granulomatous arthritis with juvenile onset: a prospective cohort study. J Clin Immunol. 2022;42(5):1089-1101.
Schwartz DT, Lee RJ, Ahmed Z, Kimura Y. Systemic manifestations of familial granulomatous arteritis: systematic review and meta-analysis. Pediatrics. 2019;144(2):e20182843.
Medication Comparisons
Compare medications used to treat Arteritis Familial Granulomatous With Juvenile Polyarthritis C1862510. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy