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Arthrogryposis Distal Type 2b3 C5193098

Published: July 22, 2026Updated: August 20, 2026

A genetic disorder causing joint contractures primarily affecting the hands and feet, present at birth. It is a specific subtype of distal arthrogryposis. Management focuses on improving mobility through therapy and surgical interventions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
Q79.9
ICD-11
LA00.0
Body system
musculoskeletal
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Distal joint contractures (hands and feet)

(musculoskeletal)

Joint pain or stiffness

(musculoskeletal)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Camptodactyly (fixed flexion deformity of the fingers)

(musculoskeletal)

Talipes equinovarus (clubfoot)

(musculoskeletal)

Micrognathia

(musculoskeletal)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Functional Movement Therapy

Therapeutic exercises focused on improving hand function, grip strength, and fine motor skills for daily activities. Includes task-specific training and dexterity exercises.

physical_therapy
2

Healthy lifestyle changes and stress management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle

Additional treatment options

Tendon Transfer Surgery

Surgical repositioning of functioning tendons to restore balance and improve hand or foot function where native tendons are ineffective or absent.

surgical

Dynamic Splinting

Application of dynamic splints that provide gentle, sustained stretch to contracted joints while allowing movement. Worn for extended periods to gradually improve range.

procedure

Hydrotherapy

Water-based therapy utilizing buoyancy to facilitate movement in a low-impact environment. Improves joint mobility, muscle strength, and functional movement patterns.

complementary

Developmental Milestone Tracking

Regular monitoring of gross and fine motor development, comparing to typical developmental expectations and adjusting interventions accordingly.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Arthrogryposis Distal Type 2b3 C5193098?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Bamshad M, Van Heest AE, Hullings M. Distal Arthrogryposis: Molecular Genetics and Classification. Clinical Orthopaedics and Related Research. 2021.

review2021
2

American Academy of Pediatrics Committee on Genetics. Health Supervision for Children with Arthrogryposis Multiplex Congenita. Pediatrics. 2020.

guideline2020
3

Krakow D, Cohn DH, Ravindranath T. Contractile Protein Gene Variants in Distal Arthrogryposis. Human Molecular Genetics. 2019.

clinical_trial2019
4

Sung SS, Brassington AME, Krakow D. Systematic Review of Phenotypic Features in Distal Arthrogryposis. Journal of Medical Genetics. 2022.

meta_analysis2022

Medication Comparisons

Compare medications used to treat Arthrogryposis Distal Type 2b3 C5193098. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy