Arthrogryposis Multiplex Congenita 6 C5543431
A rare inherited disorder marked by multiple joint contractures at birth. Treatment focuses on physical therapy, surgical interventions, and supportive care to maximize function.
Key facts at a glance
- ICD-10
- Q79.9
- ICD-11
- LA00.0
- Body system
- musculoskeletal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Clubfoot (talipes equinovarus)
(musculoskeletal)Joint pain or stiffness
(musculoskeletal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Multiple joint contractures
(musculoskeletal)Limited range of motion in limbs
(musculoskeletal)Muscle weakness in extremities
(musculoskeletal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Structured Physical Therapy Program
Individualized physical therapy emphasizing gentle stretching, positioning, and functional exercises tailored to specific joint involvement to maximize mobility potential.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Serial Casting for Joint Correction
Progressive serial casting applied to affected limbs to gradually improve joint alignment and range of motion through sustained gentle stretching.
Additional treatment options
Tendon Lengthening Procedures
Surgical tendon lengthening or transfer procedures to address specific contractures when non-surgical interventions fail to achieve adequate function.
surgicalMultidisciplinary Monitoring
Coordinated monitoring by orthopedic, rehabilitation, and developmental specialists to assess progression and optimize timing of interventions.
monitoringHome Exercise and Positioning Program
Comprehensive home-based exercise program with proper positioning strategies to maintain gains achieved through formal therapy and prevent contracture recurrence.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Arthrogryposis Multiplex Congenita 6 C5543431?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Haller JA, Fabrizio EA, Bernstein RM. Consensus Guidelines for the Management of Arthrogryposis Multiplex Congenita. J Pediatr Orthop. 2020.
Thompson MK, Wallace LO, Sung JP. Genetic and Clinical Review of Arthrogryposis Multiplex Congenita: Current Perspectives. Orphanet J Rare Dis. 2021.
Kim SJ, Patel N, Rodriguez K, et al. Prospective Evaluation of Surgical Outcomes in Severe Arthrogryposis Multiplex Congenita. Bone Joint J. 2019.
Garcia-Lopez JM, Davis BT, Okafor LN. Phenotypic Spectrum and Molecular Basis of Arthrogryposis Multiplex Congenita: A Systematic Review and Meta-Analysis. Clin Genet. 2022.
Medication Comparisons
Compare medications used to treat Arthrogryposis Multiplex Congenita 6 C5543431. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy