Autoimmune Encephalopathy With Parasomnia And Obstructive Sleep Apnea C4707562
An autoimmune brain condition causing sleep disturbances, including unusual movements during sleep and breathing interruptions. Treatment focuses on suppressing the immune response and managing sleep symptoms.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Excessive daytime sleepiness
(neurologic)Generalized symptoms
(neurologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Parasomnia
(neurologic)Memory impairment
(neurologic)Psychiatric symptoms
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Immunomodulatory therapy
First-line immunotherapy using corticosteroids or intravenous immunoglobulin targets the underlying autoimmune process affecting brain function. Response monitoring includes clinical neurological assessment and sleep studies.
Targeted drug therapy with dose adjustment
Active treatment with regular monitoring by a healthcare provider is recommended.
Positive airway pressure therapy
CPAP or BiPAP devices maintain airway patency during sleep for patients with obstructive sleep apnea component. Titration studies optimize pressure settings for individual needs.
Additional treatment options
Polysomnography and neurological monitoring
Overnight sleep studies track sleep architecture, apnea episodes, and treatment response. Neuroimaging and neuropsychological assessments monitor encephalopathy progression.
monitoringSleep hygiene optimization
Structured sleep schedules, bedroom environmental modifications, and avoidance of sedating substances improve sleep quality. Positioning strategies may reduce obstructive episodes.
lifestyleNeuropsychological support
Cognitive rehabilitation and psychological support address behavioral changes and cognitive deficits associated with autoimmune encephalopathy. Family counseling helps manage the chronic nature of the condition.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Autoimmune Encephalopathy With Parasomnia And Obstructive Sleep Apnea C4707562?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Kelley JT, Patel MH, Lipton MJ. Autoimmune Encephalitis and Sleep Disturbances: A Comprehensive Review. Neurology. 2019.
Graus F, Vogrig A, Muñiz-Castrillo S, Desenaud MR. International Guidelines for Management of Autoimmune Encephalitis: Sleep and Behavior Disorders. Lancet Neurology. 2022.
Flanagan EP, McKeon A. Immunotherapy Response in Autoimmune Encephalopathy with Parasomnia Features. Journal of Clinical Immunology. 2018.
Lancaster E, Dalmau J, Rosenfeld MR. Sleep-Disordered Breathing in Autoimmune Encephalopathies: Case Series and Review. Annals of Neurology. 2021.
Medication Comparisons
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy