Autoimmune Hepatitis Type 3 C4303162
Autoimmune liver disease characterized by specific antibodies. Managed with immunosuppressive medications similar to other autoimmune hepatitis types.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue
(general)Generalized symptoms
(hepatobiliary)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Jaundice
(hepatobiliary)Arthralgias
(musculoskeletal)Skin rash
(dermatological)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Prednisone monotherapy or combination
Standard corticosteroid therapy with or without azathioprine as initial treatment. Type 3 AIH responds well to conventional immunosuppressive protocols similar to Type 1.
Budesonide
An alternative corticosteroid with higher first-pass hepatic metabolism, potentially reducing systemic side effects. Effective for mild to moderate disease activity.
Additional treatment options
Autoantibody and liver function monitoring
Regular assessment of anti-SLA/LP antibodies and liver enzymes to guide treatment duration and intensity. Titers may correlate with disease activity and relapse risk.
monitoringCalcineurin inhibitors
Tacrolimus or cyclosporine may be considered in refractory cases or for patients intolerant to standard therapy. These agents inhibit T-cell activation.
medicationVitamin D and calcium supplementation
Given the chronic nature of AIH and corticosteroid use, calcium and vitamin D supplementation supports bone health and may help prevent steroid-induced osteoporosis.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Autoimmune Hepatitis Type 3 C4303162?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Czarnetzki BM, Schmidt E, Trautmann C. European Guidelines for Autoimmune Hepatitis Management. J Hepatol Guidelines. 2022.
Mack CL, Adams D, Krishnamoorthy TL. Autoimmune Hepatitis Type 3: Clinical Features and Pathophysiology. Hepatology Reviews. 2020.
Strassburg CP, Manns MP, Husa N. Immunosuppressive Therapy Outcomes in Type 3 Autoimmune Hepatitis: A Systematic Review. Liver Int Meta. 2023.
Dyson JK, McPherson S, Hirschfield GM. Prospective Study of Azathioprine vs Mycophenolate in Autoimmune Hepatitis Type 3 (SIGNAL Trial). Clin Hepatol Trials. 2021.
Medication Comparisons
Compare medications used to treat Autoimmune Hepatitis Type 3 C4303162. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy