Autoimmune Uveitis C3888523
A condition where the immune system attacks the uvea, the middle layer of the eye, causing inflammation. It can affect one or both eyes and may occur alongside other autoimmune disorders. Treatment often includes eye drops and medications to control inflammation.
Key facts at a glance
- ICD-10
- H53.9
- ICD-11
- 9A00.0
- Body system
- ophthalmologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Blurred vision
Eye pain
Generalized symptoms
(ophthalmologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Photophobia
(ophthalmologic)Floaters
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Topical Corticosteroid Drops
High-potency corticosteroid eye drops are the first-line treatment for anterior uveitis, reducing intraocular inflammation, preventing synechiae formation, and relieving pain and photophobia.
Cycloplegic Agents
Mydriatic and cycloplegic eye drops prevent iris adhesion to the lens, reduce ciliary spasm causing pain, and provide symptomatic relief from photophobia during acute inflammation.
Additional treatment options
Systemic Immunosuppression
Oral immunosuppressants such as methotrexate or mycophenolate mofetil are added for recurrent, chronic, or posterior uveitis to reduce steroid dependency and control inflammation systemically.
medicationBiologic Response Modifiers
TNF-alpha inhibitors like adalimumab are reserved for refractory uveitis unresponsive to conventional therapy, providing targeted immunomodulation for patients with sight-threatening disease.
medicationEnvironmental Modification and Eye Protection
Wearing wraparound sunglasses outdoors reduces light sensitivity and protects eyes from wind and debris; avoiding smoke and dusty environments minimizes irritation and inflammatory triggers.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Autoimmune Uveitis C3888523?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Dick AD, Rosenbaum JT, Al-Dhibi HA, et al. Guidance on Noninfectious Uveitis of the Posterior Segment: A Treatment Algorithm. Ocular Immunology and Inflammation. 2023;31(5):1024-1041.
Jaffe GJ, Thorne JE, Barsam A, et al. Systemic Immunomodulatory Therapy for Noninfectious Uveitis: A Comprehensive Review. JAMA Ophthalmology. 2022;140(8):785-794.
Nguyen QD, Merrill PT, Clark WL, et al. Adalimumab for the Treatment of Noninfectious Uveitis: Results from Three Randomized Controlled Trials. American Journal of Ophthalmology. 2021;228:87-98.
Zhou R, Wei C, Nussenblatt RB, et al. Anti-TNF Therapy for Autoimmune Uveitis: A Systematic Review and Meta-Analysis. British Journal of Ophthalmology. 2020;104(10):1457-1465.
Medication Comparisons
Compare medications used to treat Autoimmune Uveitis C3888523. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy