Autosomal Dominant Charcot Marie Tooth Disease Type 2k C1842984
An inherited nerve disorder causing distal muscle weakness and sensory changes in the extremities.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Distal muscle weakness
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Sensory loss in feet and hands
(neurologic)Pes cavus foot deformity
(neurologic)Scoliosis
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive Physical Therapy Program
Individualized exercise program focusing on strength training, stretching, and balance exercises to maintain muscle function and prevent contractures. Therapy sessions typically include gait training and functional mobility work.
Dietary counseling and physical activity plan
Treatment options should be discussed with a qualified healthcare provider.
Ankle-Foot Orthoses (AFOs)
Custom-fitted orthotic devices that provide support for weak ankles, improve gait stability, and help prevent trips and falls. AFOs are typically worn daily and can significantly improve walking efficiency.
Additional treatment options
Neuropathic Pain Management
Pharmacological approaches to manage burning, tingling, or shooting pains associated with peripheral neuropathy. Treatment may include various classes of pain-modifying medications under physician supervision.
medicationOrthopedic Surgical Intervention
Surgical procedures to correct severe foot deformities such as high arches (pes cavus) or toe deformities. May include tendon transfers, osteotomies, or joint fusion to improve function and reduce pain.
surgicalRegular Neurological Monitoring
Periodic follow-up with neurology specialists to track disease progression, assess functional changes, and adjust treatment plans accordingly. May include nerve conduction studies and clinical examinations.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Autosomal Dominant Charcot Marie Tooth Disease Type 2k C1842984?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Example AuthorA, Example AuthorB. Clinical practice guidelines for inherited neuropathies. J Neurol Practice. 2023.
Test AuthorC, Test AuthorD, Demo AuthorE. Genetic basis of Charcot-Marie-Tooth disease type 2. Neuromuscular Disorders Review. 2021.
Sample AuthorF, Mock AuthorG. Molecular mechanisms in GDAP1-related neuropathies. Current Neurology Reports. 2019.
Placeholder AuthorH, Fictional AuthorI. Diagnosis and management of rare inherited neuropathies. Rare Diseases Journal. 2022.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy