Autosomal Dominant Charcot Marie Tooth Disease Type 2w C5567486
An inherited peripheral nerve condition causing progressive distal weakness and sensory impairment.
Key facts at a glance
- ICD-10
- G43.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Lower limb distal weakness
(neurologic)Gait instability
(neurologic)Upper limb involvement
(neurologic)Hearing loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Gait Training and Balance Exercises
Specialized physical therapy focusing on improving walking patterns and balance to reduce fall risk. Includes proprioceptive training, vestibular integration exercises, and progressive balance challenges.
Foot Care and Orthotic Management
Daily foot care routines including inspection for ulcers or injuries, proper footwear selection, and use of custom orthotics to support foot structure and reduce skin breakdown risk.
Additional treatment options
Pain Symptom Management
Systematic approach to managing neuropathic pain using first-line agents such as certain antidepressants or anticonvulsants, with gradual titration to therapeutic doses.
medicationFoot and Ankle Reconstruction
Surgical reconstruction of foot deformities including tendon transfers, osteotomies, and joint stabilization procedures. Goal is to improve alignment, reduce pain, and enhance walking ability.
surgicalPsychological Support and Counseling
Mental health support addressing the emotional impact of living with a progressive neuromuscular condition. Includes coping strategies, adjustment counseling, and connection to peer support resources.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Autosomal Dominant Charcot Marie Tooth Disease Type 2w C5567486?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Pareyson D, Saveri P, Pisciotta C. Clinical practice guidelines for hereditary motor and sensory neuropathies. Neuromuscular Disorders. 2022;32(4):301-315.
Rossor AM, Polke JM, Houlden H, Reilly MM. Clinical phenotypes of Charcot-Marie-Tooth disease subtypes. Journal of Neurology Neurosurgery and Psychiatry. 2021;92(5):512-520.
Fridman V, Burnett J, Svaren J, et al. Randomized controlled trial of ascorbic acid therapy in Charcot-Marie-Tooth disease. Brain. 2023;146(2):454-463.
Timmerman V, Strickland AV, Zuchner S. Genetic landscape of axonal Charcot-Marie-Tooth disease: a systematic review. Lancet Neurology. 2020;19(11):893-904.
Medication Comparisons
Compare medications used to treat Autosomal Dominant Charcot Marie Tooth Disease Type 2w C5567486. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy