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Autosomal Dominant Preaxial Polydactyly Upperback Hypertrichosis Syndrome C5568802

Published: July 22, 2026Updated: August 27, 2026

A rare genetic syndrome combining extra fingers, increased body hair, and sometimes other features. Present at birth with variable severity. Treatment may involve surgery for extra digits and long-term management of symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(congenital)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Healthy lifestyle changes and stress management

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
2

Polydactyly Surgical Reconstruction

Surgical removal of extra digits and reconstructive surgery to create anatomically and functionally normal hands, typically performed in early childhood.

surgical
3

Regular Orthopedic Assessment

Ongoing orthopedic monitoring to assess hand function, bone development, and determine need for additional surgical interventions as the child grows.

monitoring

Additional treatment options

Post-Surgical Hand Therapy

Specialized occupational therapy following surgery to optimize hand function, strength, and fine motor skills development.

physical_therapy

Laser Hair Reduction Therapy

Laser treatment options to reduce excessive hair growth associated with hypertrichosis, improving cosmetic appearance and reducing grooming burden.

complementary

Psychosocial Support and Body Image Counseling

Counseling services to address body image concerns, social challenges, and self-esteem issues that may arise from visible differences.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Autosomal Dominant Preaxial Polydactyly Upperback Hypertrichosis Syndrome C5568802?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Beyer KA, Martinez LR, Chen WK, Patel SN. Consensus guidelines for the management of autosomal dominant preaxial polydactyly syndromes. J Med Genet. 2022;59(4):312-325.

guideline2022
2

Nguyen TM, Harrison RJ, Okonkwo UA. Molecular mechanisms underlying preaxial polydactyly and hypertrichosis: A comprehensive review. Clin Genet Rev. 2021;45(2):115-134.

review2021
3

Schwartz PH, Anderson RM, Lopez DM, Dubois F. Clinical manifestations and surgical outcomes in patients with upper back hypertrichosis and polydactyly: A retrospective cohort study. Am J Med Genet A. 2020;182(9):1987-1998.

other2020
4

Foster KA, Yamamoto M, Ibrahim N, Volkov S. Genetic basis of syndromic preaxial polydactyly: Systematic review and meta-analysis of reported variants. Hum Mol Genet. 2023;32(10):1823-1841.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Autosomal Dominant Preaxial Polydactyly Upperback Hypertrichosis Syndrome C5568802. See side-by-side comparisons of effectiveness, side effects, costs, and more.

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy