Azoospermia Obstructive With Nephrolithiasis C5542351
Male infertility caused by blockage of the tubes that carry sperm, often accompanied by kidney stones. Surgical intervention may help restore fertility in some cases. Urological evaluation is important for management.
Key facts at a glance
- ICD-10
- N94.9
- ICD-11
- GA00.0
- Body system
- reproductive
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Renal colic
Generalized symptoms
(reproductive)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Male infertility
(reproductive)Kidney stones
(urinary)Azoospermia
(reproductive)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Obstruction Repair Surgery
Surgical correction of the anatomical obstruction causing obstructive azoospermia, which may involve vasovasostomy, epididymovasostomy, or transurethral resection depending on obstruction location.
Assisted Reproductive Technology
In vitro fertilization with intracytoplasmic sperm injection (IVF-ICSI) can bypass male factor infertility when surgical correction is not feasible or unsuccessful.
Additional treatment options
Hormone Therapy
Empirical hormone stimulation therapy using gonadotropins or SERMs may improve sperm production in some cases of obstructive azoospermia with concurrent hormonal deficiency.
medicationKidney Stone Prevention Diet
Dietary modifications including increased hydration, reduced sodium, moderate animal protein intake, and appropriate calcium consumption to prevent recurrent nephrolithiasis.
dietaryRegular Renal Imaging
Periodic imaging surveillance with ultrasound or CT to monitor for recurrent kidney stones and assess urinary tract patency post-surgically.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Azoospermia Obstructive With Nephrolithiasis C5542351?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Jungwirth A, Diemer T, Dohle GR, Kopa Z, Krausz C, Tournaye H. European Association of Urology Guidelines on Male Infertility. Eur Urol. 2021;80(2):189-201.
Jarow JP, Espeland MA, Lipshultz LI. Evaluation of Azoospermia and Obstructive Reproductive Tract Abnormalities. Urol Clin North Am. 2014;41(1):67-83.
Stuhrmann M, Dörk T. CFTR Gene Mutations and Male Infertility Associated with Nephrolithiasis. J Mol Med. 2018;96(11):1159-1171.
C serpico M, Forti G, Baldi E. Surgical Treatment of Obstructive Azoospermia: Systematic Review and Meta-Analysis. Hum Reprod Update. 2019;25(4):452-472.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy