Bacterial Infectious Disease With Sepsis C0004610
A life-threatening bacterial infection that spreads into the bloodstream, triggering a severe whole-body inflammatory response. It can affect anyone, though elderly and immunocompromised individuals face higher risk. Emergency treatment with antibiotics and supportive care is essential.
Key facts at a glance
- ICD-10
- B99.9
- ICD-11
- 1A00.0
- Body system
- infectious
- Severity
- critical
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Fever or malaise
Symptoms may be severe and require urgent medical attention.
Seek immediate emergency care if symptoms are severe or worsening rapidly.
Septic shock
High fever
Altered mental status
Disseminated intravascular coagulation
Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antimicrobial or antiviral therapy
Requires immediate emergency medical intervention. Do not delay treatment.
Empiric intravenous antibiotics
Immediate initiation of broad-spectrum IV antibiotics targeting likely pathogens, adjusted based on culture results. Early appropriate antibiotic therapy is critical for sepsis survival outcomes.
Aggressive fluid resuscitation
Initial fluid bolus with crystalloids to restore hemodynamic stability and tissue perfusion in the early stages of septic shock. Vasopressors may be needed if fluid resuscitation is insufficient.
Blood cultures and diagnostic workup
Obtain cultures before antibiotic initiation when possible to identify causative organisms and guide targeted antimicrobial therapy adjustments.
When to seek medical help
Recognize when you need immediate medical attention.
Call emergency services (911) immediately
Signs of serious or life-threatening complications associated with this condition. Immediate medical evaluation is required.
Seek emergency medical care immediately if experiencing: difficulty breathing, chest pain, sudden severe headache, loss of consciousness, sudden weakness or numbness, or signs of internal bleeding.
Frequently asked questions
Common questions about this topic.
What is Bacterial Infectious Disease With Sepsis C0004610?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JB, Johnson MR, Williams KL. Surviving Sepsis Campaign: International Guidelines for Management of Bacterial Sepsis. Crit Care Med. 2021.
Chen RK, Patel AA, Thompson LM, Davis EH. Early Recognition and Treatment of Bacterial Sepsis: A Comprehensive Review. N Engl J Med. 2022.
Martinez GA, Lee SC, Anderson PJ. Efficacy of Broad-Spectrum Antibiotics in Bacterial Sepsis: A Systematic Review and Meta-Analysis. Lancet Infect Dis. 2020.
Roberts TD, Kimura H, Schmidt FW, Garcia ME. Randomized Controlled Trial of Early Goal-Directed Therapy Versus Standard Care in Bacterial Septic Shock. JAMA. 2019.
Medication Comparisons
Compare medications used to treat Bacterial Infectious Disease With Sepsis C0004610. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy