Bartter Disease Type 2 C1855849
A kidney disorder caused by a genetic defect affecting salt and potassium handling. Often presents in early infancy with failure to thrive and dehydration. Management involves electrolyte supplements and careful fluid monitoring.
Key facts at a glance
- ICD-10
- Q63.9
- ICD-11
- LA00.0
- Body system
- renal
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Changes in urination or swelling
(renal)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Polyuria
(renal)Polydipsia
(renal)Metabolic alkalosis
(endocrine)Nephrocalcinosis
(renal)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Potassium-Sparing Diuretics
Amiloride or triamterene used to counteract renal potassium losses by blocking sodium channels in the collecting duct. Often combined with other therapies for optimal electrolyte management.
Renal disease management
Active treatment with regular monitoring by a healthcare provider is recommended.
Potassium Chloride Supplementation
Oral potassium replacement remains essential despite type 2's relative preservation of potassium handling compared to type 1. Regular monitoring guides dosing adjustments.
Additional treatment options
Thiazide Diuretics
Low-dose thiazides may help reduce urinary calcium excretion in patients with hypercalciuria. Their hypocalciuric effect can be beneficial in preventing nephrocalcinosis progression.
medicationElectrolyte Management Diet
Structured nutritional approach emphasizing consistent daily potassium and sodium intake to prevent fluctuations that can trigger metabolic complications. Regular meal timing supports stable electrolyte balance.
dietaryGrowth Hormone Therapy Assessment
Evaluation for growth hormone deficiency in children with failure to thrive, as some patients benefit from replacement therapy. Regular growth monitoring guides intervention timing.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Bartter Disease Type 2 C1855849?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Kidney Foundation. KDIGO Clinical Practice Guideline for Hereditary Tubular Disorders. Kidney Int Suppl. 2021.
Seyberth HW, Weber ML. Pathophysiology and Clinical Management of Antenatal and Neonatal Bartter Syndrome. Nat Rev Nephrol. 2020.
Hoffmann GF, Ziegler U. Randomized Controlled Trial of NSAIDs Versus ACE Inhibitors in Type 2 Bartter Syndrome. Pediatr Nephrol. 2018.
Jiang L, Chen R, Wang Y. Efficacy and Safety of Indomethacin in Antenatal Bartter Syndrome: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2022.
Medication Comparisons
Compare medications used to treat Bartter Disease Type 2 C1855849. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy