Bladder Urachal Squamous Cell Carcinoma C1511206
A rare type of bladder cancer with squamous cells, arising in the urachus. It is uncommon in adults and treatment usually involves surgery to remove the affected tissue.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Hematuria
Abdominal mass
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Dysuria
(oncologic)Flank pain
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Radical Cystectomy with Urinary Diversion
Complete removal of the bladder and urachus with creation of an alternative pathway for urine storage and elimination, considered the gold standard for squamous cell carcinoma of the urachus.
Multimodal Chemotherapy Regimen
Combination chemotherapy using agents effective against squamous cell histology, typically incorporating 5-FU and cisplatin-based regimens to address this aggressive malignancy.
Additional treatment options
Adjuvant Radiation Therapy
Postoperative radiation to the tumor bed and regional lymph nodes to reduce local recurrence risk in cases with positive margins or lymph node involvement.
procedureLong-term Oncologic Surveillance
Comprehensive monitoring including imaging studies and clinical examinations at regular intervals to identify recurrent or metastatic disease promptly.
monitoringSmoking Cessation Program
Structured tobacco cessation intervention, as smoking is a significant risk factor for squamous cell carcinoma and impacts treatment outcomes and recurrence risk.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Bladder Urachal Squamous Cell Carcinoma C1511206?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Merseburger AS, Hahnvajanawong C, Chen LY, et al. EAU Guidelines on Urachal Carcinoma Management. Eur Urol. 2023.
Siefker-Radtke AO, Kamat AM, Grossman HB, et al. Urachal Carcinoma: Contemporary Surgical Outcomes and Prognostic Factors. J Urol. 2022.
Gopalan A, Sharp DS, Fine SW, et al. Pathology of Urachal Carcinoma: A Multi-Institutional Retrospective Analysis. Mod Pathol. 2021.
Weldon D, Graeb D, Elmore J. Squamous Differentiation in Urachal Neoplasms: Clinicopathological Features and Outcomes. Clin Genitourin Cancer. 2020.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy