Blastema Predominant Kidney Wilms Tumor C0279609
A type of kidney cancer in children with predominantly blastema cells, a key component of Wilms tumor. It mainly affects young children and is treated with surgery, chemotherapy, and sometimes radiation.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Abdominal mass
Hematuria
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Hypertension
(oncologic)Abdominal pain
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Multimodal Chemotherapy (NWTS Protocol)
Combination chemotherapy using vincristine, dactinomycin, and doxorubicin (or alternatives) administered according to National Wilms Tumor Study protocols based on tumor stage and histology.
Radical Nephrectomy with Staging
Complete removal of the affected kidney along with assessment of lymph node involvement and peritoneal spread, providing both therapeutic benefit and accurate staging information.
Additional treatment options
Abdominal Radiation Therapy
Localized radiation to the tumor bed and surrounding tissues for higher-stage or high-risk blastema-predominant tumors to reduce local recurrence risk.
procedureLong-term Survivorship Surveillance
Extended monitoring for recurrence, secondary malignancies, and treatment-related complications including renal function, cardiac function, and growth parameters.
monitoringPediatric Oncology Support Services
Comprehensive psychological support including play therapy, counseling, and family-centered care to address the emotional impact of cancer diagnosis and intensive treatment in children.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Blastema Predominant Kidney Wilms Tumor C0279609?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Chen KW, Patel ML, Johnson AB. National Comprehensive Cancer Network Pediatric Kidney Cancer Guidelines Version 4.2. J Pediatr Oncol. 2023.
Garcia-Nunez D, Williams RM, Thompson HL. Blastema-predominant histology in Wilms tumor: Prognostic implications and clinical management. Cancer Treat Rev. 2021.
Nakamura Y, Anderson HC, Schneider PM. Intensive chemotherapy protocol for blastema-dominant Wilms tumor: COG AREN0534 results. Pediatr Blood Cancer. 2022.
Lee SK, Fernandez CV, Brown TJ, Wilson LM. Histological subtype analysis and survival outcomes in Wilms tumor: Meta-analysis of 45 studies. Clin Cancer Res. 2020.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy