Bleeding Diathesis Due To A Collagen Receptor Defect C5190736
A bleeding disorder caused by defective platelet receptors for collagen, leading to impaired clotting and excessive bleeding or bruising.
Key facts at a glance
- ICD-10
- D64.9
- ICD-11
- 3A00.0
- Body system
- hematologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Easy bruising
(hematologic)Generalized symptoms
(hematologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Gingival bleeding
(hematologic)Hemarthrosis
(hematologic)Muscle hematoma
(hematologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Antifibrinolytic therapy
Administration of tranexamic acid or aminocaproic acid to inhibit fibrinolysis and stabilize blood clots in patients with bleeding tendency due to collagen receptor defects affecting platelet adhesion.
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Pre-procedural hemostatic planning
Multidisciplinary coordination with hematology and surgical teams to implement prophylactic hemostatic measures before surgical or invasive procedures, including antifibrinolytics and desmopressin when appropriate.
Additional treatment options
Desmopressin administration
Intravenous or intranasal desmopressin (DDAVP) to release von Willebrand factor and factor VIII from endothelial cells, temporarily improving platelet adhesion in some collagen receptor defects.
medicationBleeding precautions and injury prevention
Implementation of environmental modifications, protective equipment, and activity modifications to minimize trauma risk including soft-bristle toothbrushes, protective padding, and avoidance of contact sports.
lifestylePlatelet function and bleeding assessment
Regular laboratory monitoring of platelet count, function tests, and clinical bleeding assessment to evaluate disease stability and response to therapeutic interventions.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Bleeding Diathesis Due To A Collagen Receptor Defect C5190736?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
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Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy