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Blepharocheilodontic Syndrome 1 C4551988

Published: July 22, 2026Updated: August 27, 2026

A genetic syndrome causing cleft lip/palate, dental abnormalities, and eyelid malformations, affecting facial development.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

ICD-10
Q89.9
ICD-11
LA00.0
Body system
congenital
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Cleft lip and palate

(dental)

Generalized symptoms

(congenital)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Dental anomalies

(dental)

Eyelid coloboma

(ophthalmological)

Macrostomia

(facial)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Lifestyle modification and dietary intervention

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Orbital and eyelid reconstruction surgery

Surgical correction of eyelid abnormalities and facial structure defects associated with the syndrome. Typically performed in stages during childhood to optimize functional and aesthetic outcomes.

surgical

Additional treatment options

Multidisciplinary developmental monitoring

Regular assessment by genetics, ophthalmology, plastic surgery, and dental specialists to track growth and plan interventions appropriately.

monitoring

Psychological support and counseling

Counseling services to address potential social challenges, self-esteem concerns, and adjustment issues that may arise from visible facial differences.

psychological

Speech and language therapy

Evaluation and treatment of potential speech or oral motor difficulties that may be associated with lip and dental abnormalities.

complementary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Medication Comparisons

Compare medications used to treat Blepharocheilodontic Syndrome 1 C4551988. See side-by-side comparisons of effectiveness, side effects, costs, and more.

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy