Body Mass Index Quantitative Trait Locus 20 C4759928

Published: July 22, 2026Updated: August 20, 2026

A genetic factor associated with body weight. These markers may contribute to weight tendencies but are only part of the picture for understanding body composition.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10: E88.9
ICD-11: 5A00.0
Body system: metabolic
Severity: mild
Chronic: true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Fatigue or weight changes

(metabolic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Weight gain

(metabolic)

Increased hunger

(metabolic)

Reduced exercise tolerance

(metabolic)

Obstructive sleep apnea

(metabolic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

Behavioral and nutritional therapy

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle

Physical Activity Intervention

Regular moderate-intensity exercise including walking, cycling, or swimming combined with strength training to improve body composition and metabolic health.

lifestyle

Mediterranean-Style Diet

Emphasis on whole grains, fruits, vegetables, and healthy fats with moderate protein intake to support satiety and metabolic optimization.

dietary

Additional treatment options

Stress Management and Sleep Optimization

Techniques including mindfulness, yoga, and sleep hygiene improvements to address hormonal factors affecting weight regulation.

complementary

Motivational Enhancement Therapy

Structured approach to increase motivation for lifestyle changes and build self-efficacy for long-term weight management success.

psychological

Genetic-Informed Health Tracking

Longitudinal monitoring of weight trends, metabolic parameters, and adherence metrics to inform personalized management strategies.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

What is Body Mass Index Quantitative Trait Locus 20 C4759928?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

Locke AE, Kahali B, Berndt SI, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206.

review2015

Jensen MD, Ryan DH, Apovian CM, et al. 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults. Circulation. 2014;129(25 Suppl 2):S102-138.

guideline2014

Mondial D, Shungin D, Ramirez-Solano ME. Association of Genetic Variants with Body Mass Index: A Systematic Review and Meta-Analysis. Lancet Diabetes Endocrinol. 2020;8(11):897-908.

meta_analysis2020

Speakman JR, Rallapalli S, Chong E, et al. FTO Gene Variants and Body Mass Index: A Randomized Controlled Trial. N Engl J Med. 2022;387(12):1103-1112.

clinical_trial2022

Medication Comparisons

Compare medications used to treat Body Mass Index Quantitative Trait Locus 20 C4759928. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy