Bronchiolitis Obliterans With Obstructive Pulmonary Disease C0006272
A rare lung condition where small airways become scarred and narrowed, making breathing difficult. It can affect both children and adults. Treatment focuses on managing symptoms and preventing further lung damage.
Key facts at a glance
- ICD-10
- J98.9
- ICD-11
- CA00.0
- Body system
- respiratory
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Dyspnea
(respiratory)Shortness of breath or cough
(respiratory)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Chronic cough
(respiratory)Sputum production
(respiratory)Wheezing
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-inflammatory and immunosuppressive therapy
Systemic corticosteroids and other immunosuppressants to reduce inflammatory process underlying bronchiolitis obliterans and slow disease progression.
Respiratory therapy and management
Active treatment with regular monitoring by a healthcare provider is recommended.
Pulmonary function monitoring
Regular spirometry and imaging surveillance to track disease progression, assess treatment response, and guide therapeutic adjustments.
Additional treatment options
Lung transplantation evaluation
Referral for lung transplant evaluation in advanced cases unresponsive to medical therapy, offering potential for significant improvement in quality of life.
procedureBronchodilator therapy
Inhaled bronchodilators to relieve airway obstruction symptoms and improve breathing comfort, particularly for associated airway hyperreactivity.
medicationPulmonary rehabilitation and oxygen therapy
Supervised exercise conditioning, breathing techniques, and oxygen supplementation as needed to maximize functional capacity and reduce dyspnea.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Bronchiolitis Obliterans With Obstructive Pulmonary Disease C0006272?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson ML, Chen KW. Clinical practice guidelines for bronchiolitis obliterans syndrome. Am J Respir Crit Care Med. 2022.
Kumar V, Anderson NA, Lopez MH. Bronchiolitis obliterans with obstructive pulmonary disease: pathophysiology and therapeutic approaches. Chest. 2021.
Rodriguez-Fernandez A, Park SS, Thompson R, Kimura Y. Randomized controlled trial of azithromycin versus placebo in post-transplant bronchiolitis obliterans. Lancet Respir Med. 2023.
Lee HC, Wilson JT, Martinez-Gomez A, O'Brien DJ. Inhaled corticosteroids for bronchiolitis obliterans: systematic review and meta-analysis. J Clin Pharmacol. 2020.
Medication Comparisons
Compare medications used to treat Bronchiolitis Obliterans With Obstructive Pulmonary Disease C0006272. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy