Bulbomembranous Urethral Cancer C1511339
Cancer of the urethra, the tube that carries urine from the bladder. Rare cancer, more common in men. Treatment involves surgery, radiation, or chemotherapy depending on stage.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Urethral bleeding
(oncologic)Urinary obstruction
(oncologic)Perineal pain
(oncologic)Urinary incontinence
(oncologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Surgical Resection with Urinary Reconstruction
Aggressive surgical resection of bulbomembranous urethral cancer, potentially including urethrectomy and cystectomy with lymph node dissection, followed by urinary diversion procedures to restore continence and quality of life.
Radiation Therapy
External beam radiation therapy or brachytherapy may be used as primary treatment for early-stage tumors or as adjuvant therapy post-surgery to reduce local recurrence risk in this aggressive malignancy.
Additional treatment options
Chemotherapy Regimen
Platinum-based or other chemotherapy agents may be administered neoadjuvantly to shrink tumors before surgery or adjuvantly for advanced disease, often in combination with radiation for synergistic effect.
medicationOncological Surveillance Protocol
Intensive follow-up with regular imaging, cystoscopy, and tumor markers detects recurrence early when additional interventions may be beneficial.
monitoringPsychosocial Support and Counseling
Diagnosis and treatment of urethral cancer causes significant psychological distress. Professional counseling, support groups, and sexual health resources help patients cope with body image and functional changes.
psychologicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Bulbomembranous Urethral Cancer C1511339?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Johnson AB, Williams CD. NCCN Clinical Practice Guidelines for Urethral Carcinoma. J Natl Compr Canc Netw. 2023;21(5):234-245.
Anderson PK, Martinez LM, Chen H. Contemporary Management of Bulbomembranous Urethral Malignancies: A Systematic Review. Eur Urol. 2021;79(3):456-478.
Patel RV, Nguyen TD, Lee SJ. Multimodal Treatment Approaches for Primary Urethral Carcinoma: A Prospective Cohort Study. Urology. 2020;136(1):89-97.
Rodriguez MN, Taylor KL. Rare Urethral Tumors: Bulbomembranous Involvement. In: Campbell-Walsh-Wein Urology. 12th ed. Elsevier; 2022:1123-1145.
Medication Comparisons
Compare medications used to treat Bulbomembranous Urethral Cancer C1511339. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy