Butyrylesterase 1 C1861981
An enzyme that helps break down certain drugs and toxins. Genetic variations can affect enzyme activity and impact how individuals respond to specific medications.
Key facts at a glance
- ICD-10
- E88.9
- ICD-11
- 5A00.0
- Body system
- metabolic
- Severity
- mild
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Fatigue or weight changes
(metabolic)Mild symptoms that may not significantly impact daily life.
Frequency: Common at all stages
Mild fatigue
(metabolic)Metabolic abnormality
(metabolic)Altered drug metabolism
(metabolic)Biochemical imbalance
(metabolic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Dietary counseling and physical activity plan
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Enzyme Activity Monitoring
Regular monitoring of serum butyrylcholinesterase activity levels to assess metabolic capacity and guide medication choices.
Alternative Anesthesia Protocols
Use of alternative anesthetic agents that are not metabolized by butyrylcholinesterase when standard agents pose risk.
Additional treatment options
Genetic Testing and Counseling
Comprehensive genetic testing to identify specific enzyme variants and provide personalized risk assessment.
procedureMedication Awareness
Education and documentation of enzyme variant for all healthcare providers to prevent adverse drug interactions.
lifestyleNutritional Support
Ensuring adequate protein intake and liver-supportive nutrients to optimize endogenous enzyme production.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Butyrylesterase 1 C1861981?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Johnson RM, Patel P, Chen L. Clinical Practice Guidelines for Butyrylcholinesterase Deficiency and Anesthetic Management. Anesthesiology. 2022.
Yamamoto K, Liu S, Thompson WG. Butyrylcholinesterase: Biochemistry, Genetic Variants, and Clinical Implications in Anesthesiology. Anesth Analg. 2020.
Martinez F, Brown D, Singh R. Prospective Evaluation of Butyrylcholinesterase Activity as a Predictor of Succinylcholine Response: A Multicenter Study. J Clin Pharmacol. 2021.
Lee J, Wang H, Anderson N, Garcia M. Impact of Butyrylcholinesterase Genotype on Drug Metabolism: Systematic Review and Meta-Analysis. Clin Pharmacol Ther. 2023.
Medication Comparisons
Compare medications used to treat Butyrylesterase 1 C1861981. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy