C7 And C6 Deficiency Combined Subtotal C4017564
Combined C6 and C7 deficiency severely impairs immune defense against bacteria, leading to recurrent infections. Aggressive infection prevention and early treatment are essential.
Key facts at a glance
- ICD-10
- D89.9
- ICD-11
- 3A00.0
- Body system
- immunologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Severe sepsis due to Neisseria
Recurrent bacterial meningitis
Generalized symptoms
(immunologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Autoimmune hemolytic anemia
(immunologic)Chronic skin rash
(immunologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Aggressive Antibiotic Prophylaxis
Given combined C6 and C7 deficiency causing severe susceptibility to Neisseria, continuous antibiotic prophylaxis is mandatory. Consider higher-dose or alternative regimens compared to single deficiency.
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Enhanced Vaccination Protocol
Complete immunization against all relevant encapsulated organisms with serotype coverage review. Consider additional booster schedules given potentially suboptimal vaccine responses.
Additional treatment options
Intensive Infection Surveillance
More frequent monitoring than single deficiency given increased risk profile. Establish clear protocols for fever and infection management with low threshold for intervention.
monitoringRapid Response Infection Protocol
Patient carries emergency antibiotic supplies with instructions for self-treatment while seeking medical care. Medical alert bracelet essential. Family educated on IM antibiotic administration if needed.
medicationEnvironmental Infection Risk Reduction
Avoidance of crowded enclosed spaces during outbreaks, smoking cessation, and maintenance of good respiratory hygiene. Consider career and travel counseling to minimize exposure risks.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is C7 And C6 Deficiency Combined Subtotal C4017564?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalMedication Comparisons
Compare medications used to treat C7 And C6 Deficiency Combined Subtotal C4017564. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy