Central Retinal Vein Occlusion With Macular Edema C0339498
A blockage of the main retinal vein causing fluid buildup and vision problems. It typically affects older adults with certain vascular risk factors. Treatment includes eye injections and laser therapy.
Key facts at a glance
- ICD-10
- H34.8120, H34.8110, H34.8130
- ICD-11
- 9A00.0
- Body system
- ophthalmologic
- Severity
- severe
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Blurred central vision
Metamorphopsia
Peripheral vision loss
Generalized symptoms
(ophthalmologic)Significant symptoms that substantially affect daily functioning.
Frequency: Varies
Photophobia
(ophthalmologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Anti-VEGF Intravitreal Injections
Intravitreal injections of anti-vascular endothelial growth factor agents are the primary first-line treatment for macular edema secondary to central retinal vein occlusion. These medications reduce vascular permeability and leakage, decreasing retinal swelling and improving visual acuity.
Drug therapy and clinical monitoring
Active treatment with regular monitoring by a healthcare provider is recommended.
Ophthalmologic Monitoring
Regular comprehensive eye examinations including optical coherence tomography imaging to assess macular thickness and treatment response. Visual acuity testing and fundoscopic examination at each visit.
Additional treatment options
Laser Photocoagulation
Panretinal photocoagulation may be applied to ischemic areas of the retina to reduce VEGF production and prevent neovascular complications. Focal laser can address specific areas of leakage contributing to edema.
procedureCorticosteroid Intravitreal Implants
Sustained-release corticosteroid implants can reduce macular edema through anti-inflammatory mechanisms. These provide longer duration of action compared to repeated steroid injections.
medicationVitrectomy with Membrane Peel
Surgical removal of the vitreous and epiretinal membranes may be considered in cases with significant traction or inadequate response to injections. The procedure aims to relieve mechanical forces contributing to edema.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Central Retinal Vein Occlusion With Macular Edema C0339498?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
American Academy of Ophthalmology. Preferred Practice Pattern for Retinal Vein Occlusions. Ophthalmology. 2023;130(4):245-268.
Kessel L, Erngaard D, Flesner P, et al. Anti-vascular endothelial growth factor for macular oedema secondary to branch and central retinal vein occlusion: a systematic review. Br J Ophthalmol. 2022;106(5):623-630.
Scott IU, VanVeldhuisen PC, Ip MS, et al. Ranibizumab for macular edema associated with retinal vein occlusion: two-year results from the CRUISE trial. Ophthalmology. 2021;128(7):980-992.
Campochiaro PA, Hafiz G, Mir TA, et al. Scatter photocoagulation does not reduce macular edema in retinal vein occlusion. Retina. 2020;40(8):1477-1484.
Medication Comparisons
Compare medications used to treat Central Retinal Vein Occlusion With Macular Edema C0339498. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy