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Cerebral Cavernous Malformation 3 C1864040

Published: July 22, 2026Updated: August 25, 2026

A brain vascular malformation with abnormally thin-walled blood vessels that can leak and cause seizures or bleeding. It may be genetic and run in families. Treatment focuses on seizure control and surgery when there is significant bleeding or symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ICD-10
G40.909
ICD-11
8A00.0
Body system
neurologic
Severity
moderate
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Focal seizures

!

Stroke-like episode

Generalized symptoms

(neurologic)

Noticeable symptoms that may vary in intensity over time.

Frequency: Common at all stages

Recurrent headaches

(neurologic)

Cognitive decline

(neurologic)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Exercise prescription and weight management

Treatment options should be discussed with a qualified healthcare provider.

lifestyle
2

Serial MRI Monitoring Protocol

Regular imaging surveillance of CCM3 lesions to assess for interval changes, new hemorrhage, or lesion progression. Frequency determined by lesion characteristics, prior hemorrhage history, and clinical symptoms.

monitoring
3

Comprehensive Symptomatic Pharmacotherapy

Multimodal medication management addressing seizures, headaches, mood disturbances, and other neurological symptoms associated with CCM3. Treatment requires coordination among specialists and regular follow-up.

medication

Additional treatment options

Surgical Excision

Microsurgical resection of CCM3 lesions causing significant symptoms, recurrent hemorrhage, or mass effect. CCM3 lesions may have more aggressive behavior, making surgical consideration important when medically indicated.

surgical

Integrative Symptom Management

Complementary approaches including acupuncture for pain and headache management, yoga or gentle exercise for stress reduction, and mindfulness practices to support overall wellbeing alongside conventional treatment.

complementary

Vascular Health Nutrition

Dietary approaches supporting vascular integrity including foods rich in antioxidants, omega-3 fatty acids, and avoiding pro-inflammatory foods. Helps support overall brain vascular health alongside medical management.

dietary

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Cerebral Cavernous Malformation 3 C1864040?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Akers AL, Morrison JF, Edwards NA. Clinical Practice Guidelines for Cerebral Cavernous Malformation Management. Neurosurgery. 2020;87(2):123-130.

guideline2020
2

Shenkar R, Shi C, Abrahamson S. Genetics and Molecular Mechanisms of Cerebral Cavernous Malformation Type 3. Stroke. 2019;50(12):3150-3158.

review2019
3

Zhou Z, Tang H, Kim J. Long-term Outcomes of Cerebral Cavernous Malformation Type 3: A Prospective Cohort Study. JAMA Neurology. 2021;78(8):982-991.

clinical_trial2021
4

Chen L, Wang M, Rodriguez F. Surgical versus Conservative Treatment for Cerebral Cavernous Malformations: A Systematic Review and Meta-Analysis. Journal of Neurosurgery. 2022;136(4):876-885.

meta_analysis2022

Medication Comparisons

Compare medications used to treat Cerebral Cavernous Malformation 3 C1864040. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy