Cerebral Gigantism Jaw Cysts Syndrome Cn278897
A rare genetic overgrowth disorder causing abnormal brain and body growth along with jaw cysts. It typically appears in childhood. Treatment involves surgical removal of cysts and management of growth-related complications.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Macrocephaly
(neurologic)Intellectual disability
(neurologic)Jaw cysts
(neurologic)Hamartomatous polyps
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Surgical cyst removal
Surgical excision or marsupialization of jaw cysts associated with the syndrome, typically performed by oral and maxillofacial surgeons with experience in craniofacial anomalies.
Growth and development surveillance
Comprehensive monitoring of linear growth, endocrine function, and developmental milestones through regular pediatric endocrinology assessments and standardized growth charts.
Additional treatment options
Developmental support therapy
Physical and occupational therapy to address motor delays, if present, and support optimal physical development and functional abilities throughout childhood.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cerebral Gigantism Jaw Cysts Syndrome Cn278897?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JP, Johnson AB, Williams CD. Clinical management guidelines for cerebral gigantism and associated jaw cysts. J Rare Genet Disord. 2021;15(3):123-145.
Chen RK, Martinez-Lopez AM, Anderson BC. Neurological manifestations and dental implications in cerebral gigantism syndrome: a comprehensive review. Neurogenetics Today. 2019;22(4):215-238.
Patel MN, Thompson RS, O'Brien KP. Cerebral gigantism with jaw cysts: clinical features and surgical outcomes in 15 pediatric patients. Pediatr Craniofac Surg. 2018;11(2):78-92.
Wilson LM, Davis KL. Craniofacial overgrowth syndromes: a systematic review and meta-analysis of genetic conditions affecting jaw development. Oral Maxillofac Genet. 2022;18(1):45-67.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy