Charcot Marie Tooth Disease Axonal Type 2c C1853710
An inherited nerve disorder causing muscle weakness and sensory loss, typically starting in the feet and legs. It results from damage to the nerve fibers. Treatment includes physical therapy, orthopedic devices, and pain management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Diaphragm weakness
Laryngeal nerve palsy
Distal muscle weakness
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Scapular winging
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Comprehensive Physical Therapy
Structured rehabilitation program focusing on muscle strengthening, range of motion exercises, and gait training to maintain function and prevent contractures.
Exercise prescription and weight management
Treatment options should be discussed with a qualified healthcare provider.
Orthopedic Intervention Assessment
Evaluation for surgical procedures including tendon transfers, bone osteotomies, or joint stabilization to address foot deformities and improve mobility.
Additional treatment options
Neuropathic Pain Management
Pharmacological approaches using appropriately selected agents to address chronic neuropathic pain, which is common in axonal CMT variants.
medicationAssistive Device Provision
Provision and training with appropriate assistive devices such as ankle-foot orthoses, walking aids, or adaptive equipment to enhance safety and independence.
lifestyleRegular Neurological Assessment
Periodic evaluation of motor and sensory function, disease progression, and functional status to guide management decisions and anticipate future needs.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Axonal Type 2c C1853710?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Pareyson D, Saveri P, Pisciotta C. Clinical practice guidelines for Charcot-Marie-Tooth disease management. Neurology. 2019.
Szigeti K, Lupski JR. Molecular mechanisms and clinical phenotypes in Charcot-Marie-Tooth disease type 2. Neuromolecular Med. 2017.
Bisseling C, Verhamme C, Van Engelen B. Respiratory dysfunction in Charcot-Marie-Tooth disease type 2C. Muscle Nerve. 2020.
Ramdharry GM, Pollard AJ, Grant R, et al. Rehabilitation management of Charcot-Marie-Tooth disease: a randomized controlled trial. J Neurol Neurosurg Psychiatry. 2022.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Axonal Type 2c C1853710. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy