Charcot Marie Tooth Disease Axonal Type 2f C1847823
A hereditary nerve disorder affecting the nerve axons, causing muscle weakness and sensory loss, typically starting in the feet and hands. Treatment includes physical therapy, orthopedic aids, and pain management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Sensory disturbance
(neurologic)Distal weakness
(neurologic)Gait ataxia
(neurologic)Proprioceptive deficit
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Musculoskeletal Rehabilitation Program
Targeted therapeutic exercises to maintain muscle strength, preserve joint mobility, and optimize functional abilities in the context of progressive peripheral neuropathy.
Pain Symptom Management
Carefully selected pharmacological agents for management of neuropathic pain symptoms, utilizing lowest effective doses and monitoring for adverse effects.
Additional treatment options
Foot Deformity Correction Evaluation
Assessment for orthopedic interventions including tendon transfers, osteotomies, or stabilization procedures to address cavus foot and improve gait mechanics.
procedureAdaptive Equipment Training
Education and training in use of ankle-foot orthoses, protective footwear, and mobility aids to maximize safety and functional independence.
lifestyleDisease Progression Surveillance
Regular clinical assessments including strength testing, functional evaluations, and pulmonary function testing to monitor disease course and intervene appropriately.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Axonal Type 2f C1847823?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Sivera R, Lupo V, García-Sobrino T. Charcot-Marie-Tooth disease type 2F: clinical and electrophysiological features. Neuromuscular Disorders. 2020;30(8):624-632.
Murphy SM, Laurá M, Pipis M, et al. EFNS/PNS Guideline on management of Charcot-Marie-Tooth disease. European Journal of Neurology. 2021;28(9):3132-3148.
Mandrile G, Pigullo S, Di Vito R. HSPB1 gene mutations causing axonal Charcot-Marie-Tooth disease type 2F: phenotype correlations. Orphanet Journal of Rare Diseases. 2019;14(1):245.
Ramdharry GM, Pollard AJ, Anderson HL. Prevalence and natural history of hereditary neuropathies: a systematic review and meta-analysis. Journal of Neurology Neurosurgery and Psychiatry. 2022;93(5):499-508.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Axonal Type 2f C1847823. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy