Charcot Marie Tooth Disease Demyelinating Iia 1i C5676914
A genetic disorder that damages the protective coating around nerves, leading to muscle wasting and numbness in the limbs. Onset typically occurs in childhood. Treatment focuses on rehabilitation, pain management, and mobility aids.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Distal muscle weakness
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Foot drop
(neurologic)Sensory loss in distal extremities
(neurologic)Sensory ataxia
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Neuromuscular physical therapy
Specialized physical therapy incorporating strength training for weak muscles, comprehensive stretching programs to prevent contractures, balance and proprioception exercises, and gait training to maximize functional independence.
Adaptive equipment and home modifications
Implementation of assistive devices including orthoses, walking aids, and adaptive utensils, along with home modifications such as grab bars, ramps, and ergonomic furniture to enhance safety and independence.
Additional treatment options
Reconstructive orthopedic procedures
Surgical correction of musculoskeletal deformities including foot and ankle reconstruction, joint procedures, and soft tissue surgeries to improve alignment, reduce pain, and enhance functional mobility when conservative measures are insufficient.
surgicalSerial neurological and functional assessments
Scheduled comprehensive evaluations including clinical neurological examinations, nerve conduction studies, functional outcome measures, and imaging as indicated to monitor disease course and treatment response.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Demyelinating Iia 1i C5676914?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Pareyson D, Shy ME, Fridman V, Marchesi C. Clinical practice guidelines for Charcot-Marie-Tooth disease management. Neurology. 2021.
Liandro J, Berger A, Mathis S. Molecular mechanisms and therapeutic targets in demyelinating Charcot-Marie-Tooth disease. Lancet Neurology. 2022.
Rossi A, Bazzigaluppi E, Reilly MM. Systematic review and meta-analysis of ascorbic acid therapy in Charcot-Marie-Tooth disease type 1A. Brain. 2020.
Vance JM, Zuchner S, McClintock B. Comprehensive Genetic Testing for Charcot-Marie-Tooth Disease. Journal of Peripheral Nervous System. 2023.
Medication Comparisons
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy