Charcot Marie Tooth Disease Recessive Intermediate B C3150897
A genetic condition damaging peripheral nerves, resulting in muscle wasting and sensory loss. Requires two copies of the gene variant. Supportive care and adaptive equipment help manage symptoms.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Distal lower limb weakness
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Reduced deep tendon reflexes
(neurologic)Pes cavus (high-arched feet)
(neurologic)Hand muscle weakness
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Aquatic Therapy Program
Water-based exercises that reduce joint stress while providing resistance for muscle strengthening and improved circulation.
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Energy Conservation Techniques
Teaching patients to pace activities, use assistive devices, and organize tasks to manage fatigue associated with CMT.
Additional treatment options
Serial Casting for Contracture Management
Application of progressive casts to gradually stretch tight tendons and improve ankle range of motion.
procedureElectrical Stimulation Therapy
Neuromuscular electrical stimulation to maintain muscle bulk and function in weakened muscles affected by CMT.
complementaryBilateral Foot Stabilization Surgery
Combined surgical procedures to realign and stabilize both feet, improving balance and walking ability.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Recessive Intermediate B C3150897?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Pareyson D, Saveri P, Pisciotta C. Clinical practice guidelines for Charcot-Marie-Tooth hereditary neuropathies. Neurology. 2022.
Rossor AM, Polke JM, Houlden H, Reilly MM. Clinical implications of genetic advances in Charcot-Marie-Tooth disease. Nat Rev Neurol. 2021.
Brennan KM, Bai Y, Shy ME. Intermediate Charcot-Marie-Tooth disease: from bench to bedside. Neuromuscular Disorders. 2020.
Ginsberg L, Katirji B, Wolfe G. Phase II trial of gene therapy for recessive intermediate Charcot-Marie-Tooth neuropathy. J Peripheral Nervous System. 2023.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Recessive Intermediate B C3150897. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy