Charcot Marie Tooth Disease Type 2b C1833219
A hereditary nerve disorder affecting the nerve fibers, causing muscle wasting and sensory loss. Often starts in the feet and may progress. Treatment includes physical therapy, assistive devices, and pain management.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Distal lower extremity muscle weakness
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Foot deformities (pes cavus)
(neurologic)Decreased deep tendon reflexes
(neurologic)Distal sensory loss
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Muscle Conditioning and Gait Training
Targeted physical therapy emphasizing muscle strengthening, gait pattern retraining, and proprioceptive exercises to maintain functional independence and reduce fatigue.
Fall Prevention and Home Safety
Environmental modifications including grab bars, ramps, removing tripping hazards, and proper lighting to reduce fall risk and maintain independence at home.
Additional treatment options
Muscle Cramp and Spasm Relief
Management of muscle cramps and spasms associated with peripheral neuropathy using appropriate pharmacological agents based on symptom severity and patient factors.
medicationAquatic Therapy
Water-based exercise program providing resistance training with reduced joint stress, improving strength and cardiovascular fitness while minimizing injury risk.
complementaryTendon Transfer Procedures
Surgical tendon transfers to improve foot and ankle function in patients with significant weakness affecting gait mechanics and stability.
surgicalWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Type 2b C1833219?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Pareyson D, Marchesi C, Salsano E. Clinical practice recommendations for the diagnosis and management of Charcot-Marie-Tooth disease type 2. Neurology. 2019.
Shy ME, Lupski JR, Chance PF, Klein CJ. Hereditary motor and sensory neuropathies: Charcot-Marie-Tooth disease and related disorders. Nat Rev Neurol. 2021.
Banchs I, Casas E, Antonellis A, Timmerman V. Systematic review of genotype-phenotype correlations in Charcot-Marie-Tooth disease type 2. Hum Mol Genet. 2020.
Ramchandren S, Shy ME. Axonal Charcot-Marie-Tooth disease: from clinical description to genetic discovery. Neuromuscul Disord. 2022.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Type 2b C1833219. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy