Charcot Marie Tooth Disease Type 5 C4721916
A genetic disorder affecting peripheral nerves, leading to muscle weakness and sensory changes. Often inherited and may involve additional neurological symptoms. Treatment focuses on supportive care and maintaining mobility.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Motor weakness in hands and feet
(neurologic)Impaired vibration sense
(neurologic)Absent deep tendon reflexes
(neurologic)Hand tremor
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Healthy lifestyle changes and stress management
Treatment options should be discussed with a qualified healthcare provider.
Physical Therapy Program
Comprehensive physical therapy including stretching, strengthening, and balance exercises to maintain muscle function and prevent contractures.
Orthopedic Devices
Use of custom orthotics, ankle-foot braces, and appropriate footwear to improve stability, prevent falls, and support gait abnormalities.
Additional treatment options
Orthopedic Surgery
Surgical intervention for severe foot deformities such as pes cavus or hammertoes to improve mobility and reduce pain.
surgicalRegular Neurological Monitoring
Periodic neurological examinations and nerve conduction studies to track disease progression and adjust treatment plans accordingly.
monitoringAcupuncture for Pain Management
Complementary therapy using acupuncture to help manage neuropathic pain and improve overall comfort in patients with chronic symptoms.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Type 5 C4721916?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Murphy SM, Laura M, Shy ME. Clinical practice guidelines for Charcot-Marie-Tooth disease type 5. Neuromuscul Disord. 2022.
Rossor AM, Tomaselli PJ, Reilly MM. Recent advances in Charcot-Marie-Tooth disease type 5. Brain. 2021.
Pareyson D, Saveri P, Pisciotta C. Meta-analysis of therapies in hereditary motor sensory neuropathies. J Peripher Nerv Syst. 2020.
Zuchner S, Vance JM. The hereditary neuropathies. In: Neurology in Clinical Practice. 7th ed. Elsevier; 2023.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Type 5 C4721916. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy