Charcot Marie Tooth Disease Type I C0751036
A group of inherited peripheral neuropathies causing demyelination of motor and sensory nerves. Typical symptoms include distal weakness, foot deformities, and sensory loss. Physical therapy and orthopedic care are key.
Key facts at a glance
- ICD-10
- G40.909
- ICD-11
- 8A00.0
- Body system
- neurologic
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Foot drop
(neurologic)Generalized symptoms
(neurologic)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Difficulty walking
(neurologic)Upper limb involvement
(neurologic)Respiratory muscle weakness
(neurologic)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Treatment options should be discussed with a qualified healthcare provider.
Physical therapy and rehabilitation
Physical therapy is the cornerstone of CMT type 1 management, focusing on muscle strengthening, endurance training, and mobility exercises to slow disease progression and maintain function.
Orthotic intervention
Custom-made ankle-foot orthoses and specialized footwear to support weak muscles, improve walking stability, and prevent injuries from foot drop and ankle instability.
Additional treatment options
Corrective foot surgery
Surgical procedures to address high arched feet, hammertoes, and other deformities that develop due to muscle imbalance, improving function and reducing pain.
surgicalNeuropathic pain medication
Use of medications to manage neuropathic pain symptoms including burning, tingling, or shooting pains associated with peripheral nerve damage.
medicationOccupational therapy
Occupational therapy to develop strategies for daily activities, recommend adaptive equipment, and modify home and work environments to maintain independence.
complementaryWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Charcot Marie Tooth Disease Type I C0751036?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Pareyson D, Marchesi C, Salsano E. Clinical practice guidelines for Charcot-Marie-Tooth disease. Neurology. 2022.
Shy ME, Lupski JR, Chance PF, Kleopa KA. Charcot-Marie-Tooth disease: a review of genetic heterogeneity and clinical features. Lancet Neurol. 2021.
Micallef J, Attarian S, Dubourg O. Systematic review of therapeutic interventions in hereditary motor and sensory neuropathies. J Peripher Nerv Syst. 2020.
Rossor AM, Polke JM, Houlden H, Reilly MM. Clinical implications of genetic advances in Charcot-Marie-Tooth disease. Nat Rev Neurol. 2023.
Medication Comparisons
Compare medications used to treat Charcot Marie Tooth Disease Type I C0751036. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy