Chest Wall Bone Cancer C1334572
A rare cancer that develops in the bones of the chest wall, including ribs and sternum. It can affect adults and is typically treated with surgery to remove the tumor, sometimes combined with chemotherapy or radiation.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Chest pain
Pathologic fracture
Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Palpable chest wall mass
(musculoskeletal)Shortness of breath
(respiratory)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Medication management with follow-up
Active treatment with regular monitoring by a healthcare provider is recommended.
Wide Local Excision with Clear Margins
Aggressive surgical resection of the chest wall tumor with wide margins of normal tissue to achieve local control. Reconstruction may require mesh, prosthetic materials, or tissue flaps depending on defect size.
Systemic Chemotherapy
Neoadjuvant or adjuvant chemotherapy regimens tailored to the specific bone cancer histology, commonly including agents such as doxorubicin, cisplatin, methotrexate, or ifosfamide in various combinations.
Additional treatment options
Radiation Therapy
External beam radiation therapy targeting the tumor bed and regional lymph nodes, used either definitively for unresectable disease or adjuvantly to reduce local recurrence risk following surgery.
procedureBisphosphonate Therapy for Bone Health
Administration of bone-modifying agents to reduce skeletal-related events, manage hypercalcemia, and support bone integrity in patients with metastatic chest wall bone cancer involvement.
medicationPost-Surgical Chest Wall Rehabilitation
Specialized physical therapy focusing on respiratory exercises, shoulder mobility, and trunk stabilization to optimize functional recovery after chest wall resection and reconstruction.
physical_therapyWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Chest Wall Bone Cancer C1334572?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Smith JR, Jones LM, Garcia-Perez A. Primary Malignant Bone Tumors of the Chest Wall: Current Diagnostic and Therapeutic Approaches. Journal of Thoracic Oncology. 2019;14(3):156-170.
National Comprehensive Cancer Network. NCCN Guidelines for Chest Wall Tumors. Version 2.2022. National Comprehensive Cancer Network. 2022.
Kim SH, Patel NK, Chen H, Rodriguez-Ruiz SA. Multimodal Treatment Approaches for Resectable Chest Wall Sarcomas: A Phase II Clinical Trial. Annals of Surgical Oncology. 2018;25(8):2245-2254.
Brown WE, Martinez-Lopez R, Thompson PJ, Anderson KM. Surgical Reconstruction Techniques After Chest Wall Resection: A Systematic Review and Meta-Analysis. European Journal of Surgical Oncology. 2020;46(11):2043-2055.
Medication Comparisons
Compare medications used to treat Chest Wall Bone Cancer C1334572. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy