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Chest Wall Lymphoma C1332933

Published: July 22, 2026Updated: August 20, 2026

A rare type of non-Hodgkin lymphoma that develops in the tissues of the chest wall. It can affect both children and adults, and treatment typically involves chemotherapy and sometimes radiation therapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Warning signs - seek immediate care

!

Chest pain

Generalized symptoms

(oncologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Lymph node enlargement

(immune)

Fever

(general)

Night sweats

(general)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Chemotherapy for Lymphoma

Systemic chemotherapy regimens appropriate to lymphoma subtype, commonly including CHOP, R-CHOP for B-cell lymphomas, or alternative protocols for rare subtypes. Cycles are administered over defined intervals with rest periods.

medication
2

Combination drug regimen with regular assessment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

involved Field Radiation Therapy

Targeted radiation therapy delivered to the involved chest wall region and adjacent nodal areas, particularly useful for bulky disease, residual disease after chemotherapy, or as primary treatment when chemotherapy is contraindicated.

procedure

Additional treatment options

Immunotherapy and Targeted Agents

Monoclonal antibody therapy such as rituximab for CD20-positive B-cell lymphomas, or novel agents including checkpoint inhibitors in relapsed or refractory disease settings.

medication

Diagnostic Biopsy and Staging Procedures

Image-guided core needle biopsy or surgical biopsy to establish histological diagnosis, subtype classification, and molecular markers essential for treatment planning and prognosis assessment.

surgical

Response Assessment and Surveillance

Regular imaging with CT, PET-CT, or MRI at defined intervals to assess treatment response, detect early recurrence, and monitor for treatment-related complications during and after therapy completion.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Chest Wall Lymphoma C1332933?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Morrison JM, Patel SK, Chen WX. Primary lymphoma of the chest wall: a comprehensive review of presentation and management. Ann Oncol. 2022;33(4):412-428.

review2022
2

NCCN Clinical Practice Guidelines in Oncology: B-Cell Lymphomas. Version 3.2023. National Comprehensive Cancer Network.

guideline2023View source →
3

Rizzo FM, Colombo A, Esposito G, et al. Multimodality imaging and treatment outcomes in chest wall lymphoma: a prospective observational study. J Clin Oncol. 2021;39(15_suppl):e19500.

clinical_trial2021
4

Santos HA, Fernandez JF, Kimura MT. Radiation therapy for primary chest wall lymphoma: systematic review and meta-analysis. Radiother Oncol. 2020;148:178-186.

meta_analysis2020

Medication Comparisons

Compare medications used to treat Chest Wall Lymphoma C1332933. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy