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Childhood Kidney Neoplasm C1333003

Published: July 22, 2026Updated: August 20, 2026

A broad term for tumors that develop in a child's kidney, ranging from benign growths to cancerous tumors. The most common malignant type in children is Wilms tumor, which is treated with surgery and chemotherapy.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
C80.1
ICD-11
2A00.0
Body system
oncologic
Severity
severe
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Abdominal mass

(gastrointestinal)

Generalized symptoms

(oncologic)

Significant symptoms that substantially affect daily functioning.

Frequency: Common at all stages

Hypertension

(cardiovascular)

Hematuria

(genitourinary)

Weight loss

(general)

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Surgical Tumor Resection

Primary surgical approach to remove kidney neoplasms, ranging from partial to radical nephrectomy depending on tumor size, location, and pathology findings.

surgical
2

Targeted drug therapy with dose adjustment

Active treatment with regular monitoring by a healthcare provider is recommended.

medication
3

Imaging Surveillance

Regular ultrasound, CT, or MRI examinations to track tumor response to treatment, detect recurrence, or monitor stability in benign or low-grade neoplasms.

monitoring

Additional treatment options

Chemotherapy

Systemic cytotoxic medications administered to treat malignant kidney neoplasms, particularly when tumors are advanced, unresectable, or have spread beyond the kidney.

medication

Nutritional Support

Specialized dietary interventions to maintain adequate nutrition during cancer treatment, including high-calorie supplements and management of treatment-related appetite changes.

dietary

Psychosocial Support Services

Comprehensive psychological and social support including counseling, play therapy, and family support to address the emotional impact of kidney neoplasm diagnosis and treatment on children and families.

psychological

When to seek medical help

Recognize when you need immediate medical attention.

See a doctor within 24 hours

Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.

Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Childhood Kidney Neoplasm C1333003?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

National Cancer Institute Children's Oncology Group. Renal Tumors of Childhood: National Comprehensive Cancer Network Clinical Practice Guidelines. Pediatr Oncol. 2022.

guideline2022
2

Fernandez CV, Grier HE. Molecular Biology and Targeted Therapy of Pediatric Kidney Tumors. J Pediatr Hematol Oncol. 2020.

review2020
3

Dix DB, Seibel NL, Chi YY, et al. Treatment of Stage IV Favorable Histology Wilms Tumor: Children's Oncology Group Study AREN0532. J Clin Oncol. 2021.

clinical_trial2021
4

Hwang SM, Kim JY, Park SY, Lee JW. Comparative Efficacy of Multimodal Therapy Versus Monotherapy in Pediatric Renal Cell Carcinoma: A Systematic Review and Meta-Analysis. Cancer Med. 2023.

meta_analysis2023

Medication Comparisons

Compare medications used to treat Childhood Kidney Neoplasm C1333003. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy