Childhood Kidney Wilms Tumor C1333015
The most common childhood kidney cancer, usually occurring in children under age 5. With modern treatment combining surgery, chemotherapy, and sometimes radiation, outcomes are generally favorable.
Key facts at a glance
- ICD-10
- C80.1
- ICD-11
- 2A00.0
- Body system
- oncologic
- Severity
- severe
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Abdominal mass
(gastrointestinal)Generalized symptoms
(oncologic)Significant symptoms that substantially affect daily functioning.
Frequency: Common at all stages
Hypertension
(cardiovascular)Hematuria
(genitourinary)Flank pain
(genitourinary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Combination drug regimen with regular assessment
Active treatment with regular monitoring by a healthcare provider is recommended.
Nephrectomy with Lymph Node Sampling
Surgical removal of the kidney containing the Wilms tumor along with sampling of regional lymph nodes for accurate staging and to guide further treatment decisions.
Multi-Agent Chemotherapy
Combination chemotherapy using agents such as vincristine, actinomycin D, and doxorubicin to treat Wilms tumor, with regimens tailored to tumor stage and histology.
Additional treatment options
Preoperative Chemotherapy
Neoadjuvant chemotherapy administered before surgery to shrink large Wilms tumors, making surgical removal safer and more feasible while also treating micrometastatic disease.
procedureLong-Term Survivorship Care
Ongoing monitoring for recurrence, secondary malignancies, and treatment-related late effects including cardiac function, renal function, and growth abnormalities.
monitoringRenal-Protective Nutrition
Dietary modifications to support kidney health during and after treatment, including controlled protein intake, sodium management, and adequate hydration.
dietaryWhen to seek medical help
Recognize when you need immediate medical attention.
See a doctor within 24 hours
Moderate to severe symptoms that may indicate worsening of this condition. Prompt medical evaluation is recommended.
Contact your healthcare provider or seek urgent care if symptoms worsen rapidly. Go to the emergency department for life-threatening symptoms.
Frequently asked questions
Common questions about this topic.
What is Childhood Kidney Wilms Tumor C1333015?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
National Wilms Tumor Study Group. Children's Oncology Group Renal Tumor Committee. NWTSG/COG Renal Tumor Guidelines 2020. Pediatr Blood Cancer. 2020;67(S3):S1-S25.
Spreafico F, Bellani S, Collini P. Wilms Tumor: Current Concepts and Future Perspectives on Clinical, Biological, and Therapeutic Aspects. Cancers. 2022;14(3):593.
Graf N, Gnekow AK, Furtwängler R, et al. Preoperative Chemotherapy for Bilateral Wilms Tumor: SIOP 93-01 Prospective Study. J Clin Oncol. 2018;36(24):2518-2525.
Polanco PM, Went MP, Hu M, et al. Multimodal Treatment of Anaplastic Wilms Tumor: A Systematic Review and Meta-analysis. Eur Urol Oncol. 2021;4(5):782-791.
Medication Comparisons
Compare medications used to treat Childhood Kidney Wilms Tumor C1333015. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy