Cholestasis Intrahepatic Of Pregnancy 3 C3554241
A liver condition during pregnancy where bile flow is reduced, causing itching. It mainly affects pregnant women and typically resolves after delivery.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- mild
- Chronic
- false
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Generalized symptoms
(hepatobiliary)Mild symptoms that may not significantly impact daily life.
Frequency: Varies
Pruritus (itching)
(hepatobiliary)Dark urine
(hepatobiliary)Light-colored stools
(hepatobiliary)Fatigue
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Behavioral and nutritional therapy
Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.
Ursodeoxycholic Acid
This bile acid medication is the first-line treatment for intrahepatic cholestasis of pregnancy, helping reduce bile acid levels and relieve symptoms. It has been shown to improve liver function and reduce fetal risks.
Enhanced Fetal Surveillance
Regular non-stress tests, biophysical profiles, and Doppler studies monitor fetal well-being due to increased risk of complications. Monitoring intensity increases as pregnancy progresses.
Additional treatment options
Vitamin K Supplementation
Vitamin K is prescribed to address potential malabsorption issues and reduce bleeding risk associated with cholestasis. Particularly important as pregnancy approaches term.
medicationLow-Fat Nutritional Modifications
Reducing dietary fat intake decreases bile production demands on the liver, potentially easing symptoms. Focus on lean proteins, complex carbohydrates, and adequate hydration.
dietarySymptom Management Techniques
Cool baths, loose cotton clothing, and topical anti-itch creams help manage pruritus symptoms. Avoiding heat and excessive scratching prevents skin damage.
lifestyleWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cholestasis Intrahepatic Of Pregnancy 3 C3554241?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Society for Maternal-Fetal Medicine. Intrahepatic cholestasis of pregnancy: ACOG Practice Bulletin No. 211. Obstet Gynecol. 2022.
Kong X, Chen Q, Xie Y, Li J. Ursodeoxycholic acid for intrahepatic cholestasis of pregnancy: a systematic review and meta-analysis. Hepatology. 2021.
Chen L, Singh V, Lee JM, et al. Randomized controlled trial of ursodeoxycholic acid versus placebo in early-onset intrahepatic cholestasis of pregnancy. Gastroenterology. 2019.
Williamson C, Geenes V, Dixon P, Reyes H. Clinical manifestations and long-term outcomes in intrahepatic cholestasis of pregnancy: a 10-year cohort study. J Hepatol. 2020.
Medication Comparisons
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View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy