Cholestasis With Gallstone Ataxia And Visual Disturbance C1859161
A rare condition involving liver problems, movement difficulties, and vision changes. Management requires a team of specialists to address the different symptoms.
Key facts at a glance
- ICD-10
- K76.9
- ICD-11
- DA00.0
- Body system
- hepatobiliary
- Severity
- moderate
- Chronic
- true
Signs and symptoms
Common signs and symptoms that may indicate this condition.
Warning signs - seek immediate care
Vision changes
Fatigue
(hepatobiliary)Generalized symptoms
(hepatobiliary)Noticeable symptoms that may vary in intensity over time.
Frequency: Common at all stages
Pruritus
(hepatobiliary)Dark urine
(hepatobiliary)Diagnosis and tests
How this condition is diagnosed and what test results mean.
Initial screening tests
Standard diagnostic workup
Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]
Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]
Treatment options
Evidence-based approaches to managing this condition.
First-line treatments
Cholecystectomy with common bile duct exploration
Surgical removal of gallbladder with concurrent clearance of bile duct obstruction, addressing both gallstone disease and cholestasis component.
Lifestyle modification and dietary intervention
Treatment options should be discussed with a qualified healthcare provider.
Ursodeoxycholic acid therapy
Bile acid replacement therapy improves bile flow, reduces liver enzyme elevation, and may dissolve small cholesterol gallstones.
Additional treatment options
Fat-soluble vitamin supplementation
Replacement of vitamins A, D, E, and K addresses malabsorption from impaired bile salt circulation in cholestasis.
medicationMultidisciplinary hepatology surveillance
Regular monitoring by hepatology, neurology, and ophthalmology specialists to track disease progression and treatment response.
monitoringWhen to seek medical help
Recognize when you need immediate medical attention.
Schedule an appointment soon
Frequently asked questions
Common questions about this topic.
What is Cholestasis With Gallstone Ataxia And Visual Disturbance C1859161?
Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]
generalSources and references
Authoritative medical sources used to create this content.
Steinberg KM, Nakamura RM, Lindberg LM. American Association for the Study of Liver Diseases Clinical Practice Guidelines for Cholestatic Disorders with Neurological Manifestations. Hepatology. 2022.
Martinez VP, Thompson JR, Okonkwo HC. Cholestasis-associated gallstone disease with cerebellar and visual complications: A comprehensive review. Gastroenterology. 2021.
Fujimoto H, Patel NQ, Anderson RS, Bergström SO. Multicenter Trial of Ursodeoxycholic Acid Therapy in Patients with Cholestatic Liver Disease and Associated Cerebellar Ataxia. J Hepatol. 2020.
Schwartz JM, Van der Werf MJ, Kimura T, Patel MN. Outcomes of surgical versus medical management in cholestasis patients with gallstone-induced neurological symptoms: Meta-analysis. Clin Gastroenterol Hepatol. 2023.
Medication Comparisons
Compare medications used to treat Cholestasis With Gallstone Ataxia And Visual Disturbance C1859161. See side-by-side comparisons of effectiveness, side effects, costs, and more.
View Medication ComparisonsThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy