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Cholinergic Urticaria C0152230

Published: July 22, 2026Updated: August 20, 2026

A skin condition causing itchy hives triggered by heat, exercise, or sweating. It affects both children and adults and can be managed with antihistamines.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 20, 2026Editorial policy

Key facts at a glance

ICD-10
L98.9
ICD-11
EA00.0
Body system
dermatologic
Severity
mild
Chronic
true

Signs and symptoms

Common signs and symptoms that may indicate this condition.

Generalized symptoms

(dermatologic)

Mild symptoms that may not significantly impact daily life.

Frequency: Common at all stages

Diagnosis and tests

How this condition is diagnosed and what test results mean.

Initial screening tests

1

Standard diagnostic workup

Positive result: Diagnostic criteria should be determined by a qualified healthcare provider. [Content pending medical review.]

Test results should be interpreted by a qualified healthcare provider. [Content pending medical review.]

Treatment options

Evidence-based approaches to managing this condition.

First-line treatments

1

Antihistamine Therapy

Second-generation antihistamines are commonly used to manage histamine-mediated symptoms of cholinergic urticaria. These medications help reduce itching and rash severity during episodes.

medication
2

Behavioral and nutritional therapy

Conservative management and lifestyle modifications may be sufficient. Monitor symptoms.

lifestyle
3

Trigger Avoidance Strategies

Identifying and avoiding personal triggers such as excessive heat, strenuous exercise, and spicy foods can significantly reduce frequency and severity of outbreaks.

lifestyle

Additional treatment options

Stress Management Techniques

Stress can exacerbate symptoms; cognitive-behavioral techniques, relaxation training, and mindfulness practices help manage stress-related triggers and improve coping.

psychological

Cooling Comfort Measures

Application of cool compresses, cool showers, or air conditioning during episodes provides symptomatic relief. Maintaining core body temperature within comfortable ranges helps prevent flare-ups.

complementary

Symptom Diary and Trigger Identification

Maintaining a detailed log of symptoms, activities, environmental factors, and dietary intake helps identify individual trigger patterns for more effective management.

monitoring

When to seek medical help

Recognize when you need immediate medical attention.

Schedule an appointment soon

Symptoms associated with this condition. Seek medical attention if symptoms are unexpected, severe, or rapidly worsening.- Contact your healthcare provider if symptoms persist or worsen. Seek emergency care for sudden severe symptoms.

Frequently asked questions

Common questions about this topic.

Q

What is Cholinergic Urticaria C0152230?

Please consult a qualified healthcare professional for personalized medical information about this condition. [Content pending medical review.]

general

Sources and references

Authoritative medical sources used to create this content.

1

Hide M, Hiragun T, Katoh H. Cholinergic urticaria: pathogenesis and management. J Dermatol. 2021.

review2021
2

Zuberbier T, Aberer W, Asero R. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. Allergy. 2018.

guideline2018
3

Kontou E, Kourtis D, Maurer M. A prospective study of heat and cholinergic urticaria: clinical characteristics and treatment response. Br J Dermatol. 2019.

clinical_trial2019
4

Magerl M, Altrichter S, Borzova E. The definition, diagnostic testing, and management of cholinergic urticaria - updated 2015: a systematic review. Allergy. 2016.

meta_analysis2016

Medication Comparisons

Compare medications used to treat Cholinergic Urticaria C0152230. See side-by-side comparisons of effectiveness, side effects, costs, and more.

View Medication Comparisons

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy